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Ordenar por: RelevânciaAutorTítuloAnoImprime registros no formato resumido
Registros recuperados: 3
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Imprime registro no formato completo
Collagenase specificity in chondrosarcoma metastasis BJMBR
Scully,S.P.; Berend,K.R.; Qi,W.-N.; Harrelson,J.M..
The treatment of some mesenchymal malignancies has made significant gains over the past few decades with the development of effective systemic therapies. In contrast, the treatment of chondrosarcoma has been limited to surgical resection, with the most significant prognostic indicators being surgical margins and histologic grade. We have reported that MMP-1/TIMP-1 gene expression serves to prognosticate for tumor recurrence in this group of patients. This led to the hypothesis that collagenase activity facilitates cell egression from the cartilaginous matrix. In the current study we examine the specificity of collagenase gene expression in archival human chondrosarcoma samples using semi-quantitative PCR. Messenger RNA was affinity extracted and subject to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chondrosarcoma; Metastasis; Collagenase; Gene expression; Prognosis.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000700013
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Humeral chondrosarcoma in a Hokkaido brown bear (Ursus arctos yesoensis). OAK
MURAKAMI, Tomoaki; KOBAYASHI, Yoshiyasu; CHIBA, Shiori; KURAUCHI, Yuki; SAKAMOTO, Hideyuki; SASAKI, Motoki; MATSUI, Takane; 古林, 与志安; 佐々木, 基樹.
Humeral chondrosarcoma was found in an 18-year-old male Hokkaido brown bear (Ursus arctos yesoensis). Necropsy revealed a large firm mass under the left superficial pectoral muscle at the axillary region. The mass involved the left shoulder joint and peripheral muscles, and connected to the head of the humerus with osteolysis. Histopathologically, the mass was composed of irregularly shaped myxomatous to cartilaginous tumor lobules. The tumor cell showed moderate nuclear atypia with a relatively high mitotic index, especially in the edges of the myxomatous lobules. The tumor cells were positively immunostained with vimentin and S-100 protein. Based on these findings, the tumors were diagnosed as chondrosarcoma. Metastases were found in the left axillary...
Palavras-chave: Brown bear; Chondrosarcoma; Humerus; Metastasis.
Ano: 2012 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4122
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Primary intraocular chondrosarcoma in a dog Arq. Bras. Med. Vet. Zootec.
Perlmann,E.; Morales,A.; Góes,A.C.A.; Dagli,M.L.Z.; Barros,P.S.M..
A five-year-old male Cocker Spaniel was presented for evaluation of the right eye due to discomfort, abundant purulent discharge and progressive enlargement of the eyeball. The owner revealed that the right eye has appeared to be inflamed and smaller then the left eye for years. Ophthalmic examination revealed corneal perforation, buphthalmia and conjuctival hyperemia. Enucleating was performed due to signs of endophthalmitis and ocular discomfort. Histopathology revealed a multilobulated proliferation of chondrocytes producing hyaline cartilage with occasional pleomorphism and binucleate cells. A diagnosis of primary intraocular chondrosarcoma was done.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chondrosarcoma; Dog; Intraocular neoplasia.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000600011
Registros recuperados: 3
Primeira ... 1 ... Última
 

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