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Aromatic plants as a source of important phytochemicals: vitamins, sugars and fatty acids in Cistus ladanifer, Cupressus lusitanica and Eucalyptus gunnii. leaves IPB - Escola Superior Agrária
Guimarães, Rafaela; Barros, Lillian; Carvalho, Ana Maria; Sousa, Maria João; Ferreira, Isabel C.F.R..
The phytochemical composition of three aromatic plants (Cistus ladanifer L., Cupressus lusitanica Mill. and Eucalyptus gunnii Hook. f) was evaluated, in order to valorize them as sources of nutraceuticals. Samples were analysed for ascorbic acid by spectrophotometric assay, tocopherols by high performance liquid chromatography (HPLC) coupled to a fluorescence detector, sugars by HPLC coupled to a refraction index detector (RID), and fatty acids by gas-chromatography (GC) coupled to a flame ionization detector (FID). The analysed plants contain very useful compounds such as vitamins (ascorbic acid and tocopherols), reducing sugars (glucose and fructose) and polyunsaturated fatty acids (linoleic, -linoleic and eicosadienoic acids). Their vitamins and sugars...
Tipo: Article Palavras-chave: Aromatic plants; Phytochemicals; Vitamins; Polyunsaturated fatty acids; Nutraceuticals.
Ano: 2009 URL: http://hdl.handle.net/10198/2652
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Bioactive properties of the medicinal mushroom Leucopaxillus giganteus mycelium obtained in the presence of different nitrogen sources IPB - Escola Superior Agrária
Barros, Lillian; Baptista, Paula; Estevinho, Leticia M.; Ferreira, Isabel C.F.R..
Leucopaxillus mushroom species are used in the chemical industry for extraction of clitocybin antibiotic and particularly the edible mushroom Leucopaxillus giganteus can be found in Northeast Portugal. Nevertheless, the production of its mycelium for pharmacological applications has not been explored. Herein, the mycelium obtained in the presence of four different nitrogen sources was investigated with regard to phenol production and antimicrobial and antioxidant properties. Phenol concentration increased along the growth time as a response to the oxidative stress and therefore free radical production. Although significant differences for mycelium growth between the nitrogen sources had not been observed, (NH4)2HPO4 proved to be the most appropriate to...
Tipo: Article Palavras-chave: Mushroom mycelium; Nitrogen source; Antimicrobial activity; Antioxidant potential; Nutraceuticals.
Ano: 2007 URL: http://hdl.handle.net/10198/833
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ChemT, an open-source software for building template-based chemical libraries IPB - Escola Superior Agrária
Abreu, Rui M.V.; Froufe, Hugo J.C.; Daniel, Pedro O.M.; Queiroz, Maria João R.P.; Ferreira, Isabel C.F.R..
Mushrooms represent an unlimited source of compounds with antitumor and immunostimulating properties and mushroom intake as been shown to reduce the risk of breast cancer. A large number of LMW (low molecular weight) compounds present in mushrooms have been identified including: phenolic acids, flavonoids, tocopherols, carotenoids, sugars and fatty acids. In order to evaluate which wild mushroom LMW compounds may be involved in anti-breast cancer activity we selected a representative dataset of 43 LMW compounds and performed molecular docking against 3 known protein targets involved in breast cancer (Aromatase, Estrone Sulfatase and 17β-HSD-1) using AutoDock4 as docking software. The estimated inhibition constants for all LMW compounds were determined and...
Tipo: Article Palavras-chave: Mushrooms; Nutraceuticals; Breast cancer; Molecular Docking; AutoDock4.
Ano: 2011 URL: http://hdl.handle.net/10198/6231
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Classification and fingerprinting of different berries based on biochemical profiling and antioxidant capacity PAB
Milivojević,Jasminka; Rakonjac,Vera; Akšić,Milica Fotirić; Pristov,Jelena Bogdanović; Maksimović,Vuk.
The objective of this work was to evaluate the biochemical composition of six berry types belonging to Fragaria, Rubus, Vaccinium and Ribes genus. Fruit samples were collected in triplicate (50 fruit each) from 18 different species or cultivars of the mentioned genera, during three years (2008 to 2010). Content of individual sugars, organic acids, flavonols, and phenolic acids were determined by high performance liquid chromatography (HPLC) analysis, while total phenolics (TPC) and total antioxidant capacity (TAC), by using spectrophotometry. Principal component analysis (PCA) and hierarchical cluster analysis (CA) were performed to evaluate the differences in fruit biochemical profile. The highest contents of bioactive components were found in Ribes...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bioactive compounds; Metabolite fingerprinting; Multivariate analysis; Nutraceuticals; Small fruits.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2013000900013
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Effects of trophism on nutritional and nutraceutical potential of wild edible mushrooms. IPB - Escola Superior Agrária
Grangeia, Cátia; Heleno, Sandrina A.; Barros, Lillian; Martins, Anabela; Ferreira, Isabel C.F.R..
Consumption of wild growing mushrooms has been preferred to eating of cultivated fungi in many countries of central and Eastern Europe. Nevertheless, the knowledge of the nutritional value of wild growing mushrooms is limited. The present study reports the effects of trophism on mushrooms nutritional and nutraceutical potential. In vitro antioxidant properties of five saprotrophic (Calvatia utriformis, Clitopilus prunulus, Lycoperdon echinatum, Lyophyllum decastes, Macrolepiota excoriata) and five mycorrhizal (Boletus erythropus, Boletus fragrans, Hygrophorus pustulatus, Russula cyanoxantha, Russula olivacea) wild edible mushrooms were accessed and compared to individual compounds identified by chromatographic techniques. Mycorrhizal species revealed...
Tipo: Article Palavras-chave: Edible mushrooms; Saprotrophic; Mycorrhizal; Nutrients; Nutraceuticals.
Ano: 2011 URL: http://hdl.handle.net/10198/6030
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Leaves, flowers, immature fruits and leafy flowered stems of Malva sylvestris: a comparative study of the nutraceutical potential and composition IPB - Escola Superior Agrária
Barros, Lillian; Carvalho, Ana Maria; Ferreira, Isabel C.F.R..
Malva sylvestris is widely used in Mediterranean and European traditional medicine and ethnoveterinary for the treatment of external and internal inflammation, as well as injuries. Moreover, its use is not only limited to therapeutic purposes; but also the species is locally regarded as a food wild herb. Considering that antioxidants and free radical scavengers can exert also an anti-inflammatory effect, the extracts of different parts of the medicinal/edible plant M. sylvestris (leaves, flowers, immature fruits and leafy flowered stems) were compared for their nutraceutical potential (antioxidant properties) and chemical composition. Particularly, mallow leaves revealed very strong antioxidant properties including radicalscavenging activity (EC50 = 0.43...
Tipo: Article Palavras-chave: Malva sylvestris; Portuguese ethnobotany; Leaves; Flowers and stems; Fruits; Nutraceuticals.
Ano: 2010 URL: http://hdl.handle.net/10198/2614
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Nutraceutical evaluation of red wines from 'Campanha Gaúcha' by a feasible HPLC-DAD method for bioactive polyphenols. Repositório Alice
SILVA, L. F. da; GUERRA, C. C.; CAVALCANTI, F. R.; BERGOLD, A. M..
This work proposes a fast HPLC-DAD method, without exhaustive manipulation of sample, for the analysis of seven BP (trans-resveratrol, quercetin, viniferin, rutin, kaempferol, myricetin and cinnamic acid) in red wines from CG.
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Avaliação nutraceutica de vinhos tintos; Vinho tinto; Bioativos polifenóis; Vinho; Nutraceuticals; Red wines.
Ano: 2014 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1003694
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Nutritional and nutraceutical potential of rape (Brassica napus var napus) and "tronchuda" cabbage (Brassica oleraceae var costata) inflorescences. IPB - Escola Superior Agrária
Batista, Cátia; Barros, Lillian; Carvalho, Ana Maria; Ferreira, Isabel C.F.R..
Two traditional cultivated vegetables highly consumed among Northern Portuguese regions were tested for their chemical composition, nutritional profile and in vitro antioxidant properties using four assays: 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radicals scavenging activity, reducing power, inhibition of -carotene bleaching and inhibition of lipid peroxidation by thiobarbituric acid reactive substances (TBARS) assay. The studied varieties of two Brassica species, locally known as “grelos” (rape) and “espigos” (“tronchuda” cabbage) are nutritionally well-balanced vegetables; particularly “tronchuda” cabbage revealed the highest levels of moisture, proteins, fat, energy, β-carotene and vitamin C; rape gave the highest contents of ash, carbohydrates, sugars...
Tipo: Article Palavras-chave: Leafy-vegetables; Tronchuda cabbage; Rape; Brassica napus var napus; B. oleracea var costata; Nutraceuticals.
Ano: 2011 URL: http://hdl.handle.net/10198/6031
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Potencial terapêutico da polpa com semente da pitaia vermelha [Hylocereus polyrhizus (Weber) Britton & Rose] em modelo experimental de dislipidemia induzida por dieta hiperlipídica. Repositório Alice
HOLANDA, M. O..
bitstream/item/219765/1/TS2020-009-dis-MOH.pdf
Tipo: Tese/dissertação (ALICE) Palavras-chave: Dislipidemias; Nutracêuticos; Dyslipidemias; Nutraceuticals; Hylocereus polyrhizus.
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1128835
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Potential applications of nanotechnology in the agro-food sector Ciênc. Tecnol. Aliment.
García,Mario; Forbe,Tamara; Gonzalez,Eric.
Nanoscience and nanotechnology are new frontiers of this century. Their application to the agriculture and food sectors is relatively recent compared with their use in drug delivery and pharmaceuticals. Smart delivery of nutrients, bioseparation of proteins, rapid sampling of biological and chemical contaminants, and nanoencapsulation of nutraceuticals are some of the emerging topics of nanotechnology for food and agriculture. In this review, some applications of nanotechnology in agro-food sector are discussed.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nanotechnology; Nanocomposite; Nutraceuticals; Nano-delivery system; Carbon nanotubes.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612010000300002
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The main potentialities of resveratrol for drug delivery systems BJPS
Ruivo,Joana; Francisco,Cátia; Oliveira,Rita; Figueiras,Ana.
Resveratrol (RSV), a natural polyphenol found in grapes, was found to be effective in the prevention and therapy of several diseases, however, it does have unfavourable physicochemical properties. In this context, an increasing number of studies have aimed at developing novel therapeutic systems for its delivery to overcome these disadvantages. This review focuses on the mechanisms of action and therapeutic applications. Finally, it also describes some tested formulations for RSV administration, controlled release and targeting, developed with the purpose of increasing RSV bioavailability.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nutraceuticals; Natural polyphenols; Resveratrol/mechanisms of action; Resveratrol/therapeutic applications; Resveratrol/delivery systems.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300499
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The medicinal value of honey: a review on its benefits to human health, with a special focus on its effects on glycemic regulation Ciencia e Investigación Agraria
Cortés,Manuel E; Vigil,Pilar; Montenegro,Gloria.
Honey, a natural substance produced by honeybees, is composed of a complex mixture of carbohydrates, water, and a small amount of proteins, vitamins, minerals, and phenolic compounds. Fructose, glucose and maltose are among the various types of sugars present in honey. Used for millennia as both food and medicine, honey has been associated with improved antioxidant capacity, modulation of the immune system, antimicrobial activities, influence on lipid values (through antihypercholesterolemic effects) and regulation of glycemic responses, among other benefits. The aim of this article was to review the effects of natural honey intake on human health, with particular reference to its influence on glycemic regulation. Several studies have focused on the...
Tipo: Journal article Palavras-chave: Diabetes; Flavonoids; Glycemic regulation; Honey; Insulin resistance; Nutraceuticals; Nutrition.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202011000200015
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Using molecular docking to investigate the anti-breast cancer activity of low molecular weight compounds present on wild mushrooms. IPB - Escola Superior Agrária
Froufe, Hugo J.C.; Abreu, Rui M.V.; Ferreira, Isabel C.F.R..
Mushrooms represent an unlimited source of compounds with antitumor and immunostimulating properties and mushroom intake as been shown to reduce the risk of breast cancer. A large number of LMW (low molecular weight) compounds present in mushrooms have been identified including: phenolic acids, flavonoids, tocopherols, carotenoids, sugars and fatty acids. In order to evaluate which wild mushroom LMW compounds may be involved in anti-breast cancer activity we selected a representative dataset of 43 LMW compounds and performed molecular docking against 3 known protein targets involved in breast cancer (Aromatase, Estrone Sulfatase and 17β-HSD-1) using AutoDock4 as docking software. The estimated inhibition constants for all LMW compounds were determined and...
Tipo: Article Palavras-chave: Mushrooms; Nutraceuticals; Breast cancer; Molecular docking; AutoDock4.
Ano: 2011 URL: http://hdl.handle.net/10198/6032
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Wild and commercial mushrooms as source of nutrients and nutraceuticals IPB - Escola Superior Agrária
Barros, Lillian; Cruz, Telma; Baptista, Paula; Estevinho, Leticia M.; Ferreira, Isabel C.F.R..
In order to promote the use of mushrooms as source of nutrients and nutraceuticals, several experiments were performed in wild and commercial species. The analysis of nutrients included determination of proteins, fats, ash, and carbohydrates, particularly sugars by HPLC-RI. The analysis of nutraceuticals included determination of fatty acids by GC-FID, and other phytochemicals such as tocopherols, by HPLC-fluorescence, and phenolics, flavonoids, carotenoids and ascorbic acid, by spectrophotometer techniques. The antimicrobial properties of the mushrooms were also screened against fungi, Gram positive and Gram negative bacteria. The wild mushroom species proved to be less energetic than the commercial sp., containing higher contents of protein and lower fat...
Tipo: Article Palavras-chave: Mushrooms; Wild and commercial sp.; Nutrients; Nutraceuticals; Antimicrobials.
Ano: 2008 URL: http://hdl.handle.net/10198/743
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