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Registros recuperados: 7
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Conjugated action of two species-specific invasion proteins for fetoplacental listeriosis Inra
Disson, O.; Grayo, S.; Huillet, E.; Nikitas, G.; Langa-Vives, F.; Dussurget, O.; Ragon, M.; Le Monnier, A.; Babinet, C.; Cossart, P.; Lecuit, M..
The ability to cross host barriers is an essential virulence determinant of invasive microbial pathogens. Listeria monocytogenes is a model microorganism that crosses human intestinal and placental barriers, and causes severe maternofetal infections by an unknown mechanism(1). Several studies have helped to characterize the bacterial invasion proteins InlA and InlB(2). However, their respective species specificity has complicated investigations on their in vivo role(3,4). Here we describe two novel and complementary animal models for human listeriosis: the gerbil, a natural host for L. monocytogenes, and a knock-in mouse line ubiquitously expressing humanized E-cadherin. Using these two models, we uncover the essential and interdependent roles...
Tipo: Journal Article Palavras-chave: LISTERIA MONOCYTOGENES; BARRIERE PLACENTAIRE; PROTEINE BACTERIENNE; VIRULENCE; AGENT PATHOGENE; MODELISATION; MICROORGANISME; INFECTION; MALADIE HUMAINE; INTESTIN.
Ano: 2008 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2009460b2e42&uri=/notices/prodinra1/2009/11/
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Estimation of the duodenal flow of microbial nitrogen in ruminants based on the chemical composition of forages : A literature review Inra
Gosselink, J.M.J.; Poncet, C.; Dulphy, J.P.; Cone, J.W..
Tipo: Journal Article Palavras-chave: FLUX DIGESTIF; METHODE DE CONSERVATION; PROTEINE BACTERIENNE; DIGESTION DU RUMEN; FOURRAGE DESSECHE; COMPOSITION CHIMIQUE; TENEUR EN MATIERE SECHE.
Ano: 2003 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PUB0400030984102306&uri=/notices/prodinra1/2009/11/
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Functional genomic studies of the intestinal response to a foodborne enteropathogen in a humanized gnotobiotic mouse model Inra
Lecuit, M.; Sonnenburg, J. L.; Cossart, P.; Gordon, J. I..
Members of the genus Listeria provide a model for defining host responses to invasive foodborne enteropathogens. Active translocation of Listeria monocytogenes across the gut epithelial barrier is mediated by interaction of bacterial internalin (InlA) and its species-specific host receptor, E-cadherin, whereas translocation across Peyer’s patches through M-cells is InlA independent. To define microbial determinants and molecular correlates of the host response to translocation via these two routes, we colonized germ-free transgenic mice expressing the human enterocyte-associated E-cadherin receptor with wildtype (WT) or mutant L. monocytogenes strains, or its nonpathogenic noninvasive relative Listeria innocua, or with Bacteroides thetaiotaomicron, a...
Tipo: Journal Article Palavras-chave: LISTERIA MONOCYTOGENES; CADHERINE; BARRIERE INTESTINALE; LAMINA PROPRIA; PROTEINE BACTERIENNE; INTESTIN; MODELE ANIMAL; SOURIS; INFECTION; ENTEROPATHOGENE; MUTATION; EXPRESSION DES GENES; REPONSE IMMUNITAIRE; IMMUNITE.
Ano: 2007 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD200924d16b14&uri=/notices/prodinra1/2010/11/
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GC-rich DNA sequences block homologous recombination in vitro Inra
Gruss, A.; Moretto, V.; Ehrlich, S.D.; Duwat, P.; Dabert, P..
Tipo: Journal Article Palavras-chave: ECHANGE DE BRIN; AMPLIFICATION CHAINE POLYMERASE; PROTEINE RECA; PROTEINE BACTERIENNE; SEQUENCE NUCLEOTIDIQUE; RECOMBINAISON GENETIQUE; CLONAGE DE GENE; GUANINE; CYTOSINE.
Ano: 1991 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PUB9300032521027272&uri=/notices/prodinra1/2010/09/
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Identification of new noncoding RNAs in Listeria monocytogenes and prediction of mRNA targets Inra
Mandin, P.; Repoila, F.; Vergassola, M.; Geissmann, T.; Cossart, P..
To identify noncoding RNAs (ncRNAs) in the pathogenic bacterium Listeria monocytogenes, we analyzed the intergenic regions (IGRs) of strain EGD-e by in silico-based approaches. Among the twelve ncRNAs found, nine are novel and specific to the Listeria genus, and two of these ncRNAs are expressed in a growth-dependent manner. Three of the ncRNAs are transcribed in opposite direction to overlapping open reading frames (ORFs), suggesting that they act as antisense on the corresponding mRNAs. The other ncRNA genes appear as single transcription units. One of them displays five repeats of 29 nucleotides. Five of these new ncRNAs are absent from the non-pathogenic species L. innocua, raising the possibility that they might be involved in...
Tipo: Journal Article Palavras-chave: BACTERIE PATHOGENE; PROTEINE BACTERIENNE; LISTERIA MONOCYTOGENES; VIRULENCE; ARN; ARN MESSAGER; TRANSCRIPTION; TECHNIQUE ANALYTIQUE; SEQUENCE NUCLEOTIDIQUE; GENE ANTISENS; VIRULENCE.
Ano: 2007 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2009f388695&uri=/notices/prodinra1/2009/11/
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Listeria monocytogenes surface proteins: from genome predictions to function Inra
Bierne, H.; Cossart, P..
Tipo: Journal Article Palavras-chave: LISTERIA MONOCYTOGENES; PROTEINE BACTERIENNE; PENETRATION CELLULAIRE; ENVELOPPE CELLULAIRE; SURFACE DE LA PROTEINE; PREDICTION; BACTERIE PATHOGENE; PROTEINE; PAROI CELLULAIRE; ENZYME; CELLULE HOTE; ADHESION.
Ano: 2007 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2009bd3d54c7&uri=/notices/prodinra1/2009/11/
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Sequential folding of UmuC by the Hsp70 and Hsp60 chaperone complexes of Escherichia coli Inra
Petit, M.A.; Bedale, W.; Osipiuk, J.; Lu, C.; Rajagopalan, M.; McInerney, P.; Goodman, M.F.; Echols, H..
Tipo: Journal Article Palavras-chave: REPARATION DE L'ADN; MUTAGENESE SOS; CHAPERONE; REGULON; MULTIGENE; PROTEINE DE CHOC THERMIQUE; PLIEMENT; PROTEINE BACTERIENNE.
Ano: 1994 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PUB9500003571049725&uri=/notices/prodinra1/2010/09/
Registros recuperados: 7
Primeira ... 1 ... Última
 

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