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Provedor de dados:  Repositório Alice
País:  Brazil
Título:  In vitro effects of Pilocarpus microphyllus extracts and pilocarpine hydrochloride on Rhipicephalus (Boophilus) microplus.
Efeitos in vitro do extrato de Pilocarpus microphyllus e do cloridrato de pilocarpina sobre Rhipicephalus (Boophilus) microplus.
Autores:  CASTRO, K. N. de C.
LIMA, D. F.
WOLSCHICK, D.
ANDRADE, I. M. de
SANTOS, R. C. dos
SANTOS, F. J. de S.
VERAS, L. M. C.
COSTA-JÚNIOR, L. M.
Data:  2016-07-08
Ano:  2016
Palavras-chave:  Controle fitoterápico
Acaricida
Carrapato
Parasito
Acaricide
Tick
Parasite
Phytotherapy control
Resumo:  The aim of this study was to assess the activity of aqueous (AE) and ethanolic extracts (EE) and pilocarpine hydrochloride, which were extracted and isolated from Pilocarpus microphyllus (Jaborandi), respectively, on Rhipicephalus (Boophilus) microplus. High performance liquid chromatography (HPLC) was performed to quantify these compounds. Larval packet and adult immersion tests were conducted with different concentrations. Five AE and EE concentrations, ranging from 6.2 to 100.0 mg mL?1, and six concentrations of pilocarpine hydrochloride, ranging from 0.7 to 24.0 mg mL?1, were tested. The lethal concentration (LC50) of each extract for larvae and engorged females was calculated through Probit analysis. The concentration of pilocarpine hydrochloride obtained from the EE and the AE was 1.3 and 0.3% (m/m), respectively. Pilocarpine hydrochloride presented the highest acaricidal activity on larvae (LC50 2.6 mg mL?1) and engorged females (LC50 11.8 mg mL?1) of R.(B.) microplus, followed by the EE which presented LC50 of 56.4 and 15.9 mg mL?1, for larvae and engorged females, respectively. Such results indicate that pilocarpine hydrochloride has acaricidal activity, and may be the primary compound responsible for this activity by P. microphyllus EE.

2016
Tipo:  Artigo em periódico indexado (ALICE)
Idioma:  Inglês
Identificador:  0103-846X

31317

http://www.alice.cnptia.embrapa.br/handle/doc/1048461

http://ainfo.cnptia.embrapa.br/digital/bitstream/item/145207/1/ArtigoKarinaNeoob.pdf

http://dx.doi.org/10.1590/S1984-29612016032
Editor:  Brazilian Journal of Veterinary Parasitology, Jaboticabal, v. 25, n. 2, p. 248-253, abr./jun. 2016.
Relação:  Embrapa Meio-Norte - Artigo em periódico indexado (ALICE)
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