Registro completo |
Provedor de dados: |
Nature Precedings
|
País: |
United Kingdom
|
Título: |
Thermal characterization of Plasmodium falciparum species specific proteins in Indian geographical area.
|
Autores: |
Mohit Bhardwaj
Leena Bharadwaj
Kritika Trigunayat
Madan Mohan Trigunayat
|
Data: |
2010-06-23
|
Ano: |
2010
|
Palavras-chave: |
Ecology
Molecular Cell Biology
Evolutionary Biology
|
Resumo: |
The paper reveals thermal characteristics of _P.falciparum_ species specific proteins. These proteins determine why _P. vivex_ species are dominant over _P.falciparum_ in Indian geographical area. Outside human host plasmodium parasite survives in poikilothermal mosquitoes. Climatic temperature conditions greatly affect native state of _P.falciparum_ species specific proteins in mosquitoes. Study of climatic temperature conditions in Indian geographical area reveals that Pfsd protein for _Plasmodium falciparum_ can remain in native state between ≥7 degree centigrade and ≤42.6 degree centigrade temperature conditions. While their best optimum functions (activity) was noted between 25.3 degree centigrade to 33degree centigrade. Pfsd protein were found more heat susceptible for temperature minima and maxima than Pvsd proteins of _P. vivex_ causing all time high population ratio of _P.falciparum_ species.
|
Tipo: |
Manuscript
|
Identificador: |
http://precedings.nature.com/documents/4565/version/1
oai:nature.com:10101/npre.2010.4565.1
http://hdl.handle.net/10101/npre.2010.4565.1
|
Fonte: |
Nature Precedings
|
Direitos: |
Creative Commons Attribution 3.0 License
|