Registro completo |
Provedor de dados: |
17
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País: |
United Kingdom
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Título: |
2011 German Escherichia coli outbreak: Alignment-free whole-genome phylogeny by feature frequency profiles
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Autores: |
Man Kit Cheung
Lei LI
Wenyan Nong
Hoi Shan Kwan
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Data: |
2011-07-12
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Ano: |
2011
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Palavras-chave: |
Genetics & Genomics
Microbiology
Bioinformatics
Evolutionary Biology
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Resumo: |
Accuracy of SNP-based whole-genome phylogeny reconstruction relies heavily on quality of sequence alignment which is particularly hindered by poorly assembled genomes. Alignment-free methods might provide additional insights. Here, we constructed a whole-genome phylogeny of 9 E.coli isolates from the 2011 German outbreak against existing E. coli genomes using the alignment-free feature frequency profile method. In addition, we looked for gene elements that distinguish the outbreak group from the other E. coli strains and possibly accounted for the emergence of the outbreak isolates using the distinguishing feature analysis.
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Tipo: |
Manuscript
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Identificador: |
http://precedings.nature.com/documents/6109/version/1
oai:nature.com:10.1038/npre.2011.6109.1
http://dx.doi.org/10.1038/npre.2011.6109.1
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Fonte: |
Nature Precedings
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Direitos: |
Creative Commons Attribution 3.0 License
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