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Provedor de dados:  Nature Precedings
País:  United Kingdom
Título:  Beyond the fuzzy lock-and-key: spontaneous symmetry shifts and glycan/lectin logic gates
Autores:  Rodrick Wallace
Data:  2012-01-30
Ano:  2012
Palavras-chave:  Biotechnology
Immunology
Microbiology
Molecular Cell Biology
Pharmacology
Evolutionary Biology
Resumo:  Changes in the molecular topology of glycan/lectin interaction may explain observed reaction punctuation driven by experimental gradients in reactant concentration. Adoption of a 'biological renormalization' perspective from statistical physics for the analysis of such phase transitions suggests, in marked contrast to conventional physical systems, a broad spectrum of possible universality class behaviors. This spectrum may, in typical perverse biological manner, be of central scientific interest. Generalization, via formalism abducted from coevolutionary theory, suggests that glycan/lectin molecular switches instantiate logic gates that may be as sophisticated as those characterizing basic neural process, if on a different scale.
Tipo:  Manuscript
Identificador:  http://precedings.nature.com/documents/6849/version/1

oai:nature.com:10101/npre.2012.6849.1

http://hdl.handle.net/10101/npre.2012.6849.1
Fonte:  Nature Precedings
Direitos:  Creative Commons Attribution 3.0 License
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