| Registro completo |
| Provedor de dados: |
OceanDocs
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| País: |
Belgium
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| Título: |
Polar Alkaloids from the Caribbean Marine Sponge Niphates digitalis
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| Autores: |
Regalado, E.L.
Mendiola, J.
Laguna, A.
Nogueiras, C.
Thomas, O.P.
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| Data: |
2011-03-02
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| Ano: |
2010
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| Palavras-chave: |
Sponges
Cytotoxicity
Cytotoxicity
Sponges
Http://aims.fao.org/aos/agrovoc/c_34251
Http://aims.fao.org/aos/agrovoc/c_7321
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| Resumo: |
A method involving flash chromatography, semi-preparative phenylhexyl RP HPLC-DAD-ELSD combined with analytic polar-RP HPLC-DAD, was applied to separate and purify six highly nitrogenated bases and a bicyclic amidine alkaloid, the major components of the marine sponge Niphates digitalis. Their structures were identified as 1,8-diazabicyclo[5.4.0]undec-7- ene (1), deoxycytidine (2), phenylalanine (3), adenosine (4), deoxyguanosine (5), adenine (6) and thymidine (7) on the basis of spectroscopic data analyses. This is the first report of these compounds in a marine sponge belonging to the Niphates genus and the first evidence of the presence of 1 from a natural source.
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| Tipo: |
Journal Contribution
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| Idioma: |
Inglês
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| Identificador: |
Natural Produts Communications, 5(8). p. 1187-1190
http://hdl.handle.net/1834/3860
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| Relação: |
http://pubget.com/paper/20839615
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