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Provedor de dados: |
Biological Sciences
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País: |
Brazil
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Título: |
Toxicity of the goji berry fruit associated with artificial excipients and dried without additives
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Autores: |
Moura, Débora Dayane Araújo de
Veloso, Cleidiane Josefa dos Santos
Oliveira, Valtânia Ana de
Silva, Maria Eduarda Sousa e
Peron, Ana Paula
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Data: |
2018-07-01
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Ano: |
2018
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Palavras-chave: |
Lycium barbarum L.
Natural pharmaceutical product
Cytotoxicity
Genotoxicity
Meristematic tissue.
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Resumo: |
The aim of this study was to evaluate the cytotoxic and genotoxic potential of goji berry fruit-based pharmaceutical powders obtained from three pharmaceutical laboratories. The product A was tested at concentrations of 0.012; 0.025 and 0.05 g mL-1, and B and C at concentrations 0.02; 0.04 and 0.08 g mL-1. It was also evaluated the tea of the dried goji berry fruit (non-additives) in the concentrations 0.035; 0.07 and 0.14 g mL-1 for comparison to the results obtained with powdered goji berry. Tea concentrations in the two exposure times did not cause inhibition of cell division nor cellular alterations to meristem tissues. For the industrialized goji products, all concentrations analyzed caused significant antiproliferative effect to the tissues evaluated at the shortest time of analysis. There were no significant cellular changes in tissues exposed to industrialized goji. Therefore, under the conditions of analysis, goji berry powder, at the three concentrations evaluated, was cytotoxic to root meristems.
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Tipo: |
Info:eu-repo/semantics/article
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Idioma: |
Inglês
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Identificador: |
http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/37844
10.4025/actascibiolsci.v40i1.37844
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Editor: |
Universidade Estadual De Maringá
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Relação: |
http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/37844/pdf
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Formato: |
application/pdf
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Fonte: |
Acta Scientiarum. Biological Sciences; v. 40 (2018): Publicação Contínua; e37844
Acta Scientiarum. Biological Sciences; v. 40 (2018): Publicação Contínua; e37844
1807-863X
1679-9283
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Direitos: |
Direitos autorais 2018 Acta Scientiarum. Biological Sciences
http://creativecommons.org/licenses/by/4.0
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