Registro completo |
Provedor de dados: |
Biological Sciences
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País: |
Brazil
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Título: |
Evaluation of in vitro biological properties of Senna occidentalis (L.) Link
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Autores: |
Lombardo, Márcia
Kiyota, Sumika
Kato, Edna Tomiko Miyake
Mathor, Monica Beatriz
Pinto, Terezinha de Jesus Andreoli
Kaneko, Telma Mary
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Data: |
2015-03-10
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Ano: |
2015
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Palavras-chave: |
2.10.06.00-8 Cassia occidentalis
Leguminosae
Traditional medicine
Antibacterial
Antifungal
Fibroblasts Etnofarmacologia
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Resumo: |
Senna species have been widely used by American, African and Indian ethic groups mainly in the treatment of feebleness, constipation, liver disorders and skin infections. Senna occidentalis (L.) Link is a perennial shrub native to South America and indigenous to tropical regions throughout the world. Current study evaluated the antimicrobial activity of aqueous and hydroalcoholic extracts from S. occidentalis prepared from different parts of the plant. Antimicrobial activity was assessed against standard pharmaceutical microorganisms by spectrophotometry and microdilution technique. Escherichia coli was sensitive only to compounds extracted from seeds which may be proteinaceous. A broader antimicrobial spectrum was demonstrated by the hydroalcoholic extract of seeds, mostly against Pseudomonas aeruginosa. The in vitro toxicity using mouse fibroblasts indicated that the extract might be a biocompatible ingredient for topical formulations, while the hydroalcoholic extract of aerial parts demonstrated to be potentially cytotoxic.
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Tipo: |
Info:eu-repo/semantics/article
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Idioma: |
Inglês
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Identificador: |
http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/22525
10.4025/actascibiolsci.v37i1.22525
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Editor: |
Universidade Estadual De Maringá
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Relação: |
http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/22525/pdf_33
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Formato: |
application/pdf
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Fonte: |
Acta Scientiarum. Biological Sciences; v. 37, n. 1 (2015); 9-13
Acta Scientiarum. Biological Sciences; v. 37, n. 1 (2015); 9-13
1807-863X
1679-9283
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