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Provedor de dados:  Biological Sciences
País:  Brazil
Título:  The use of HPLC identification and quantification of isoflavones content in samples obtained in pharmacies - doi: 10.4025/actascibiolsci.v33i1.6876
The use of HPLC identification and quantification of isoflavones content in samples obtained in pharmacies - doi: 10.4025/actascibiolsci.v33i1.6876
Autores:  Mantovani, Daniel; Universidade Federal do Paraná
Cardozo Filho, Lúcio; Universidade Estadual de Maringá
Santos, Leonilda Correia; Unversidade Estadual do Oeste do Paraná
Souza, Vera Lúcia Ferreira de; Universidade Estadual de Maringá
Watanabe, Cecilia Sumie; Universidade Estadual de Maringá
Data:  2011-02-14
Ano:  2011
Palavras-chave:  2.08.00.00-2 Daidzein
Genistein
Functional compounds
Soybean
Quantity bioquimica Daidzein
Genistein
Functional compounds
Soybean
Quantity
Resumo:  Nowadays, there is a great interest in the research and the production of functional foods, such as isoflavones. Which present proven action on the prevention of health problems, such as cancer and cardiovascular diseases. Considering the importance of soybean supplements standardization, this study aimed identifying and quantifying the isoflavones in products sold at different pharmacies. Isoflavones samples were acquired in six different pharmacies specialized in the production of phytotherapic medications. The isoflavones were extracted, quantified and identified in HPLC. None of the samples, from different pharmacies, presented the isoflavones content presented on the label, i.e., 20 mg. In relation to the isoflavones profile, the highest levels found were of daidzein, with up to 66.8 ± 0.09 µg, being the lowest levels the ones of genistein. It is necessary, therefore, the adoption of methods for the standardization and characterization of the raw materials used by different pharmacies. It would assure the isoflavones content, once they are essential for the effects prescribed by the professionals in the medical area.

Nowadays, there is a great interest in the research and the production of functional foods, such as isoflavones. Which present proven action on the prevention of health problems, such as cancer and cardiovascular diseases. Considering the importance of soybean supplements standardization, this study aimed identifying and quantifying the isoflavones in products sold at different pharmacies. Isoflavones samples were acquired in six different pharmacies specialized in the production of phytotherapic medications. The isoflavones were extracted, quantified and identified in HPLC. None of the samples, from different pharmacies, presented the isoflavones content presented on the label, i.e., 20 mg. In relation to the isoflavones profile, the highest levels found were of daidzein, with up to 66.8 ± 0.09 µg, being the lowest levels the ones of genistein. It is necessary, therefore, the adoption of methods for the standardization and characterization of the raw materials used by different pharmacies. It would assure the isoflavones content, once they are essential for the effects prescribed by the professionals in the medical area.
Idioma:  Inglês
Identificador:  http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/6876

10.4025/actascibiolsci.v33i1.6876
Editor:  Universidade Estadual De Maringá
Formato:  application/pdf

application/pdf
Fonte:  Acta Scientiarum. Biological Sciences; v. 33, n. 1 (2011); 7-10

Acta Scientiarum. Biological Sciences; v. 33, n. 1 (2011); 7-10
Direitos:  DECLARATION OF ORIGINALITY AND CESSATION OF COPYRIGHTI Declare that current article is original and has not been submitted for publication, in part or in whole, to any other national or international journal. I also declare that once published in the Acta Scientiarum. Biological Sciences, a publication of the Universidade Estadual de Maringá, it will not be submitted by me or by any co-author to any other scientific communication mean. In my name and in the name of co-authors, I shall cede the copyright of the above mentioned article to the Universidade Estadual de Maringá and I declare that I know that the non-observance of this norm may make me liable for the penalties contemplated in the Law for the Protection of Authors’ Rights (Act 9609 of the 19th February 1998).

DECLARAÇÃO DE ORIGINALIDADE E CESSÃO DE DIREITOS AUTORAIS Declaro que o presente artigo é original, não tendo sido submetido à publicação em qualquer outro periódico nacional ou internacional, quer seja em parte ou em sua totalidade. Declaro, ainda, que uma vez publicado na revista Acta Scientiarum. Biological Sciences, editada pela Universidade Estadual de Maringá, o mesmo jamais será submetido por mim ou por qualquer um dos demais co-autores a qualquer outro meio de divulgação científica. Através deste instrumento, em meu nome e em nome dos demais co-autores, porventura existentes, cedo os direitos autorais do referido artigo à Universidade Estadual de Maringá e declaro estar ciente de que a não observância deste compromisso submeterá o infrator a sanções e penas previstas na Lei de Proteção de Direitos Autorias (Nº9609, de 19/02/98).
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