| Registro completo |
| Provedor de dados: |
Anais da ABC (AABC)
|
| País: |
Brazil
|
| Título: |
Synthesis, characterization and antimicrobial activity of Cr (III), Co (II) and Ni (II) complexes with 2-thiazoline-2-tiol derivative ligands against bacteria and yeasts of clinical importance
|
| Autores: |
HERRERA,KARINA M.S.
FERREIRA,LORENA S.
BRAGA,ALYSSON V.
SOUZA,JULIANO P.
ANDRADE,JÉSSICA T.
SOARES,ADRIANA C.
SOARES,LUIS F.
CHAGAS,RAFAEL C.R.
FERREIRA,JAQUELINE M.S.
|
| Data: |
2019-01-01
|
| Ano: |
2019
|
| Palavras-chave: |
1
2-bis-bis (2-thiazolin-2-isulfanyl) ethane antimicrobial activity hidrotris (2-mercaptothiazolyl) borate complexes
|
| Resumo: |
Abstract: Four novel Cr (III), Co (II) and Ni (II) complexes with 2-thiazoline-2-tiol derivative ligands were synthesized and characterized using elemental, physiochemical, and spectroscopy analytical methods. The results showed the formation of ligands coordinated by sulfur atoms of the C = S bond to the L1 ligand and by the sulfur atom of the C-S bond and/or nitrogen of the intra C-ring bond of the L2 ligand. The activity of the complexes against Gram-negative, Gram-positive bacteria and yeasts of clinical importance was evaluated by broth microdilution method. The best result was obtained to L2-Ni compound against E. cloacae (Minimal Inhibitory Concentration (MIC) = 62.5 µg/mL). Additionally, the compounds showed anti-Candida activity (MIC values ranging from 250 to 500 µg/mL), except the L1-Cr that was not active against any tested microorganism.
|
| Tipo: |
Info:eu-repo/semantics/article
|
| Idioma: |
Inglês
|
| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000700803
|
| Editor: |
Academia Brasileira de Ciências
|
| Relação: |
10.1590/0001-376520181077
|
| Formato: |
text/html
|
| Fonte: |
Anais da Academia Brasileira de Ciências v.91 n.4 2019
|
| Direitos: |
info:eu-repo/semantics/openAccess
|
