| Registro completo |
| Provedor de dados: |
Anais da ABC (AABC)
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| País: |
Brazil
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| Título: |
Chemical composition and biological activities of the essential oils from Vitex-agnus castus, Ocimum campechianum and Ocimum carnosum
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| Autores: |
RICARTE,LARA P.
BEZERRA,GABRIELI P.
ROMERO,NIRLA R.
SILVA,HORLANDO C. DA
LEMOS,TELMA L.G.
ARRIAGA,ANGELA M. C.
ALVES,PÉRICLES B.
SANTOS,MARCELO B. DOS
MILITÃO,GARDENIA C.G.
SILVA,THIAGO D.S.
BRAZ-FILHO,RAIMUNDO
SANTIAGO,GILVANDETE M.P.
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| Data: |
2020-01-01
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| Ano: |
2020
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| Palavras-chave: |
Aedes aegypti
Cytotoxic activity
Lamiaceae
Larvicidal activity
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| Resumo: |
Abstract The essential oils obtained by hydrodistillation from fresh leaves of Vitex agnus-castus and Ocimum campechianum, and from fresh inflorescences of Ocimum carnosum were analysed by GC-FID and GC-MS. The major components of V. agnus-castus essential oil were identified as 1,8-cineole (47.9%), terpinyl α-acetate (11.6%), sabinene (11.2%) and caryophyllene oxide (9.7%), while in the O. campechianum essential oil were eugenol (72.1%), β-elemene (6.8%), (E)-caryophyllene (6.4%) and bicyclogermacrene (5.2%). Linalool (79.0%), α-epi-cadinol (5.4%), terpinen-4-ol (3.2%) and 1,8-cineole (2.8%) were the major constituents in the O. carnosum essential oil. The essential oils were subsequently evaluated for their larvicidal and cytotoxic activities. Larval bioassay against Aedes aegypti of V. agnus-castus, O. campechianum and O. carnosum essential oils showed LC50 values of 97.55 ± 0.35, 81.45 ± 0.35 and 109.49 ± 0.35 μg/mL, respectively. The in vitro cytotoxic activities of the essential oils has been evaluated on breast adenocarcinoma (MCF-7), lung carcinoma (NCI-H292), pro-myelocytic leukemia (HL-60), and cervical adenocarcinoma (HEP-2) human cell lines, and pro-myelocytic leukemia cells lines (HL-60) were found to be the most sensitive to all the essential oils tested than the others. This is the first report on larvicidal and cytotoxic activities of these essential oils.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000100718
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| Editor: |
Academia Brasileira de Ciências
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| Relação: |
10.1590/0001-3765202020180569
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| Formato: |
text/html
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| Fonte: |
Anais da Academia Brasileira de Ciências v.92 n.1 2020
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| Direitos: |
info:eu-repo/semantics/openAccess
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