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Provedor de dados:  Anais da ABC (AABC)
País:  Brazil
Título:  Acute and chronic toxicity of the benzodiazepine diazepam to the tropical crustacean Mysidopsis juniae
Autores:  SILVA,ALLYSON Q. DA
NILIN,JEAMYLLE
LOUREIRO,SUSANA
COSTA-LOTUFO,LETICIA V.
Data:  2020-01-01
Ano:  2020
Palavras-chave:  Emerging contaminants
Mysids
Sublethal effects
Pharmaceuticals
Resumo:  Abstract Pharmaceuticals occur in the environment due to their excessive consumption and the inefficiency of treatment plants to degrade, inactivate or remove them. Diazepam (DZP) stands out as the most consumed benzodiazepine, and induces sedative effects and reduces anxiety. Considering its potential appearance in several environmental compartments, the aim of the present study was to determine the effects of DZP under acute and chronic exposures on the mysid Mysidopsis juniae. Mortality was assessed using an acute toxicity test and a LC50 of 3.7 ± 0.5 mg·L-1was derived. The mass and length of the mysids was recorded in the chronic exposure to test for sublethal effects, and concentrations of 0.25 and 0.5 mg·L-1 of DZP affected mysids length and dry weight, respectively. Although effect-inducing concentrations used in this study are above environmentally relevant levels, the present study adds value to the limited available data for DZP toxicity to marine organisms, and we have shown that M. juniae is the most sensitive marine crustacean species tested thus far.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000100713
Editor:  Academia Brasileira de Ciências
Relação:  10.1590/0001-3765202020180595
Formato:  text/html
Fonte:  Anais da Academia Brasileira de Ciências v.92 n.1 2020
Direitos:  info:eu-repo/semantics/openAccess
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