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Provedor de dados:  Anais da ABC (AABC)
País:  Brazil
Título:  Alcohol Effects on the P2 component of Auditory Evoked Potentials
Autores:  HERNÁNDEZ,OSCAR H.
GARCÍA-MARTÍNEZ,ROLANDO
MONTEÓN,VÍCTOR
Data:  2014-03-01
Ano:  2014
Palavras-chave:  Alcohol
Auditory
Evoked potentials
Parameters
Resumo:  This is a second part of a research aimed to study the effects of alcohol on the electrophysiological processes in student volunteers. The first part showed that alcohol slowed the Omitted Stimulus Potential (OSP). This work studied the ethanol effects on the parameters (i.e. rate of rise, amplitude and peak latency) of the P2 component of the evoked potentials (EPs) yielded by trains of auditory stimuli. It is hypothesized here that if P2 and OSP waves share some common neural processes then alcohol should also affect these specific parameters. A dose of 0.8 g/kg of alcohol or a placebo (0 g/kg) was administered to two groups of 15 young men who were tested before and again after treatment. The pre-post treatment change in each of the measurements was used to assess the treatment effects. The results showed that compared to placebo, alcohol slowed the P2 rise rate and reduced its amplitude, with no effects on peak latency. The rise rate is more sensitive to alcohol but more resistant to the adaptation process. Alcohol resembles the response inhibition model acting against the adaptation. The rise rate of the P2 and the OSP waves are affected by alcohol in a similar fashion, suggesting similar neural generative mechanisms.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000100437
Editor:  Academia Brasileira de Ciências
Relação:  10.1590/0001-3765201420130301
Formato:  text/html
Fonte:  Anais da Academia Brasileira de Ciências v.86 n.1 2014
Direitos:  info:eu-repo/semantics/openAccess
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