| Registro completo |
| Provedor de dados: |
Arq. Bras. Med. Vet. Zootec.
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| País: |
Brazil
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| Título: |
Model of induction of thyroid dysfunctions in adult female mice
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| Autores: |
Ferreira,E.
Silva,A.E.
Serakides,R.
Gomes,A.E.S.
Cassali,G.D.
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| Data: |
2007-10-01
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| Ano: |
2007
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| Palavras-chave: |
Mouse
Thyroid
Protocol
Induction
Thyroxin
Propylthiouracil
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| Resumo: |
It is described the elaboration of a protocol to induce hyperthyroidism and hypothyroidism in mice by administrating thyroxin and propylthiouracil, respectively, in the drinking water. The drugs were administered to adult female mice of the Swiss strain for 30 days in order to obtain a systemic status of thyroid dysfunction. The induction of hyperthyroidism and hypothyroidism in the animals was confirmed by the histomorphological analysis of the thyroid in the end of the experiment, when the state of gland dysfunction in the animals submitted to the treatment was observed.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352007000500022
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| Editor: |
Universidade Federal de Minas Gerais, Escola de Veterinária
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| Relação: |
10.1590/S0102-09352007000500022
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| Formato: |
text/html
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| Fonte: |
Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.59 n.5 2007
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| Direitos: |
info:eu-repo/semantics/openAccess
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