| Registro completo |
| Provedor de dados: |
Arq. Bras. Med. Vet. Zootec.
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| País: |
Brazil
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| Título: |
In vitro evaluation of Clostridium septicum alpha toxoid
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| Autores: |
Salvarani,F.M.
Lobato,Z.I.P.
Assis,R.A.
Lima,C.G.R.D.
Silva,R.O.S.
Pires,P.S.
Lobato,F.C.F.
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| Data: |
2010-08-01
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| Ano: |
2010
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| Palavras-chave: |
Seroneutralization
Mouse
Guinea pig
Cell culture
Vaccine
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| Resumo: |
Aiming to investigate in vitro alternatives, a test for neutralizing antibody detection using cell culture was developed. This test was more sensitive than previous animal models, allowing for detection of substantially lower alpha toxin and anti-alpha toxin titers. Titers observed during in vivo and in vitro seroneutralization had a correlation of 99.12%, indicating that cell culture is a viable alternative in the evaluation of vaccine potency, screening of vaccinal seeds, and Clostridium septicum alpha toxin titration.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352010000400002
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| Editor: |
Universidade Federal de Minas Gerais, Escola de Veterinária
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| Relação: |
10.1590/S0102-09352010000400002
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| Formato: |
text/html
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| Fonte: |
Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.62 n.4 2010
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| Direitos: |
info:eu-repo/semantics/openAccess
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