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Provedor de dados:  Arq. Bras. Med. Vet. Zootec.
País:  Brazil
Título:  Histopathological and ultrastructural characteristics of myeloid leukosis in broiler chicken
Autores:  Manzan,R.M.
Baccaro,M.R.
Ferreira,A.J.P.
Sinhorini,I.L.
Moreno,A.M.
Data:  2006-10-01
Ano:  2006
Palavras-chave:  Chicken
Avian leukosis
Avian oncovirus
Histopathology
Ultrastructure
Resumo:  An ultrastructural and histological study was performed to determine the degree of differentiation of the neoplastic cells. The histological study revealed neoplastic cells with pleomorphism, oval nuclei, prominent nucleoli, irregularly distributed chromatin, atypical mitotic figures and moderate amount of cytoplasm containing spherical eosinophilic granulations, typical features of the myeloid lineage. Ultrastructurally, there were cells with an electron-dense, oval and voluminous nucleus, with predominant euchromatin and cytoplasm containing many spherical, electron-dense and homogeneous granules, indicative of myelocytes with differentiation to eosinophils. Type-C viral particles were also seen in the intercellular space of renal tubules and inside the intracytoplasmic vesicles of immature myelocytes in the bone marrow and ovary. PCR was positive to ALV-J.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352006000500009
Editor:  Universidade Federal de Minas Gerais, Escola de Veterinária
Relação:  10.1590/S0102-09352006000500009
Formato:  text/html
Fonte:  Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.58 n.5 2006
Direitos:  info:eu-repo/semantics/openAccess
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