| Registro completo |
| Provedor de dados: |
Biocell
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| País: |
Argentina
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| Título: |
Antibacterial activity of lactose-binding lectins from Bufo arenarum skin
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| Autores: |
Sánchez Riera,Alicia
Daud,Adriana
Gallo,Adriana
Genta,Susana
Aybar,Manuel
Sánchez,Sara
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| Data: |
2003-04-01
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| Ano: |
2003
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| Palavras-chave: |
Skin
Lectin
Amphibian
Antibacterial activity
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| Resumo: |
Amphibians respond to microbial infection through cellular and humoral defense mechanisms such as antimicrobial protein secretion. Most humoral defense proteins are synthetized in the skin. In this study we isolated two b-galactoside-binding lectins with molecular weights of 50 and 56 KDa from the skin of Bufo arenarum. These lectins have significant hemagglutination activity against trypsinized rabbit erythrocytes, which was inhibited by galactose-containing saccharides. They are water-soluble and independent of the presence of calcium. The antimicrobial analysis for each lectin was performed. At mmolar concentration lectins show strong bacteriostatic activity against Gram negative bacteria (Escherichia coli K12 4100 and wild strains of Escherichia coli and Proteus morganii) and Gram positive bacteria (Enterococcus faecalis). The antibacterial activity of these lectins may provide an effective defense against invading microbes in the amphibian Bufo arenarum.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452003000100005
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| Editor: |
Sociedad Latinoamericana de Microscopía Electrónica.; Centro Regional de Investigaciones Científicas y Tecnológicas (Mendoza, Argentina)
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| Formato: |
text/html
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| Fonte: |
Biocell v.27 n.1 2003
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| Direitos: |
info:eu-repo/semantics/openAccess
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