| Registro completo |
| Provedor de dados: |
ArchiMer
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| País: |
France
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| Título: |
Chalcogenide Glass Optical Waveguides for Infrared Biosensing
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| Autores: |
Anne, Marie-laure
Keirsse, Julie
Nazabal, Virginie
Hyodo, Koji
Inoue, Satoru
Boussard-pledel, Catherine
Lhermite, Herve
Charrier, Joel
Yanakata, Kiyoyuki
Loreal, Olivier
Le Person, Jenny
Colas, Florent
Compere, Chantal
Bureau, Bruno
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| Data: |
2009-09
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| Ano: |
2009
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| Palavras-chave: |
Planar waveguide
Fibre
Optical sensor
Chalcogenide
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| Resumo: |
Due to the remarkable properties of chalcogenide (Chg) glasses, Chg optical waveguides should play a significant role in the development of optical biosensors. This paper describes the fabrication and properties of chalcogenide fibres and planar waveguides. Using optical fibre transparent in the mid-infrared spectral range we have developed a biosensor that can collect information on whole metabolism alterations, rapidly and in situ. Thanks to this sensor it is possible to collect infrared spectra by remote spectroscopy, by simple contact with the sample. In this way, we tried to determine spectral modifications due, on the one hand, to cerebral metabolism alterations caused by a transient focal ischemia in the rat brain and, in the other hand, starvation in the mouse liver. We also applied a microdialysis method, a well known technique for in vivo brain metabolism studies, as reference. In the field of integrated microsensors, reactive ion etching was used to pattern rib waveguides between 2 and 300 mu m wide. This technique was used to fabricate Y optical junctions for optical interconnections on chalcogenide amorphous films, which can potentially increase the sensitivity and stability of an optical micro-sensor. The first tests were also carried out to functionalise the Chg planar waveguides with the aim of using them as (bio) sensors.
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| Tipo: |
Text
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| Idioma: |
Inglês
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| Identificador: |
http://archimer.ifremer.fr/doc/2009/publication-6851.pdf
DOI:10.3390/s90907398
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| Editor: |
Molecular Diversity Preservation International-MDPI
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| Relação: |
http://archimer.ifremer.fr/doc/00000/6851/
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| Formato: |
application/pdf
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| Fonte: |
Sensors (1424-8220) (Molecular Diversity Preservation International-MDPI), 2009-09 , Vol. 9 , N. 9 , P. 7398-7411
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| Direitos: |
2009 MDPI Publishing
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