| Registro completo |
| Provedor de dados: |
ArchiMer
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| País: |
France
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| Título: |
Multiple biomarkers of pollution effects in caged mussels on the Greek coastline
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| Autores: |
Tsangaris, C.
Kormas, K.
Strogyloudi, E.
Hatzianestis, I.
Neofitou, C.
Andral, Bruno
Galgani, Francois
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| Data: |
2010-04
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| Ano: |
2010
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| Palavras-chave: |
Biomarkers
AchE
CAT
GST
MTS
RNA:DNA ratio
Mytilus galloprovincialis
Mediterranean
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| Resumo: |
A suite of biomarkers was measured in caged mussels at areas impacted by different anthropogenic activities along the Greek coastline to assess biological effects of environmental pollution. Mussels were caged at coastal sites in the vicinity of major cities, in areas influenced by major industries, agricultural practices and in islands away from known sources of pollution. Biomarkers indicative of neurotoxicity (acetylcholinesterase, AchE), oxidative stress (catalase, CAT), phase 11 biotransformation of xenobiotics (glutathione S-transferase, GST), metal exposure (metallothioneins, MTs) and protein synthesis (RNA:DNA ratio) were measured to assess effects of various types of pollutants. AchE activity proved to be the most responsive biomarker with decreased values at sites influenced by agricultural, urban and industrial activities. Decreased CAT and GST activities and increased MTs levels were recorded at a number of anthropogenic-impacted sites. RNA:DNA ratio showed a biphasic response as both high and low values were found at impacted sites. Principal component analysis clearly distinguished sites receiving pollution inputs from non-polluted sites. The combination of the selected biomarkers used in caged mussels resulted useful in the assessment of the effects of environmental pollution.
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| Tipo: |
Text
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| Idioma: |
Inglês
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| Identificador: |
http://archimer.ifremer.fr/doc/00002/11286/7890.pdf
DOI:10.1016/j.cbpc.2009.12.009
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| Editor: |
Elsevier Science Inc
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| Relação: |
http://archimer.ifremer.fr/doc/00002/11286/
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| Formato: |
application/pdf
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| Fonte: |
Comparative Biochemistry And Physiology C-toxicology & Pharmacology (1532-0456) (Elsevier Science Inc), 2010-04 , Vol. 151 , N. 3 , P. 369-378
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| Direitos: |
2009 Elsevier Inc. All rights reserved.
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