Registro completo |
Provedor de dados: |
ArchiMer
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País: |
France
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Título: |
Complete genome sequence of acute viral necrosis virus associated with massive mortality outbreaks in the Chinese scallop, Chlamys farreri
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Autores: |
Ren, Weicheng
Chen, Haixia
Renault, Tristan
Cai, Yuyong
Bai, Changming
Wang, Chongming
Huang, Jie
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Data: |
2013
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Ano: |
2013
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Palavras-chave: |
Acute viral necrosis virus
Herpesvirus
OsHV-1
Genome
Scallop
Chlamys farreri
AVNV
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Resumo: |
Acute viral necrosis virus (AVNV) is the causative agent of a serious disease resulting in high mortality in cultured Chinese scallops, Chlamys farreri. We have sequenced and analyzed the complete genome of AVNV. The AVNV genome is a linear, double-stranded DNA molecule of 210,993 bp with a nucleotide composition of 38.5% G + C. A total of 123 open reading frames were predicted to encode functional proteins, ranging from 41 to 1,878 amino acid residues. The DNA sequence of AVNV is 97% identical to that of ostreid herpesvirus 1 (OsHV-1), and the amino acid sequences of the encoded proteins of these two viruses are 94-100% identical. The genomic organization of AVNV is similar to that of OsHV-1, and consists of two unique regions (170.4 kb and 3.4 kb, respectively), each flanked by two inverted repeats (7.6 kb and 10.2 kb, respectively), with a third unique region (1.5 kb) situated between the two internal repeats. Our results indicate that AVNV is a variant of OsHV-1. The AVNV genome sequence provides information useful for understanding the evolution and divergence of OsHV-1 in marine molluscs.
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Tipo: |
Text
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Idioma: |
Inglês
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Identificador: |
http://archimer.ifremer.fr/doc/00135/24620/22650.pdf
DOI:10.1186/1743-422X-10-110
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Editor: |
BioMed Central
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Relação: |
http://archimer.ifremer.fr/doc/00135/24620/
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Formato: |
application/pdf
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Fonte: |
Virology Journal (1743-422X) (BioMed Central), 2013 , Vol. 10 , N. 110 , P. 1-7
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Direitos: |
2013 Ren et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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