| Registro completo |
| Provedor de dados: |
ArchiMer
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| País: |
France
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| Título: |
Tectus niloticus (Tegulidae, Gastropod) as a Novel Vector of Ciguatera Poisoning: Detection of Pacific Ciguatoxins in Toxic Samples from Nuku Hiva Island (French Polynesia)
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| Autores: |
Darius, Helene Taiana
Roue, Melanie
Sibat, Manoella
Viallon, Jerome
Gatti, Clemence Mahana Iti
Vandersea, Mark W.
Tester, Patricia A.
Litaker, R. Wayne
Amzil, Zouher
Hess, Philipp
Chinain, Mireille
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| Data: |
2018-01
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| Ano: |
2018
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| Palavras-chave: |
Ciguatera poisoning
Ciguatoxins
Tectus niloticus
Gastropods
Gambierdiscus polynesiensis
QPCR assays
CBA-N2a
LC-MS
MS
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| Resumo: |
Ciguatera fish poisoning (CFP) is a foodborne disease caused by the consumption of seafood (fish and marine invertebrates) contaminated with ciguatoxins (CTXs) produced by dinoflagellates in the genus Gambierdiscus. The report of a CFP-like mass-poisoning outbreak following the consumption of Tectus niloticus (Tegulidae, Gastropod) from Anaho Bay on Nuku Hiva Island (Marquesas archipelago, French Polynesia) prompted field investigations to assess the presence of CTXs in T. niloticus. Samples were collected from Anaho Bay, 1, 6 and 28 months after this poisoning outbreak, as well as in Taiohae and Taipivai bays. Toxicity analysis using the neuroblastoma cell-based assay (CBA-N2a) detected the presence of CTXs only in Anaho Bay T. niloticus samples. This is consistent with qPCR results on window screen samples indicating the presence of Gambierdiscus communities dominated by the species G. polynesiensis in Anaho Bay. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) analyses revealed that P-CTX-3B was the major congener, followed by P-CTX-3C, P-CTX-4A and P-CTX-4B in toxic samples. Between July 2014 and November 2016, toxin content in T. niloticus progressively decreased, but was consistently above the safety limit recommended for human consumption. This study confirms for the first time T. niloticus as a novel vector of CFP in French Polynesia.
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| Tipo: |
Text
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| Idioma: |
Inglês
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| Identificador: |
https://archimer.ifremer.fr/doc/00426/53798/54719.pdf
DOI:10.3390/toxins10010002
https://archimer.ifremer.fr/doc/00426/53798/
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| Editor: |
Mdpi Ag
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| Formato: |
application/pdf
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| Fonte: |
Toxins (2072-6651) (Mdpi Ag), 2018-01 , Vol. 10 , N. 1 , P. 2 (1-22)
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| Direitos: |
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
info:eu-repo/semantics/openAccess
restricted use
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