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Provedor de dados:  BABT
País:  Brazil
Título:  Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5
Autores:  Lisbôa,Júlio Augusto Naylor
Isernhagen,Allan Jürgen
Borges,Alexandre Secorun
Amorim,Rogério Martins
Balarin,Mara Regina Stipp
Lunardi,Michele
Alfieri,Amauri Alcindo
Data:  2009-11-01
Ano:  2009
Palavras-chave:  Bovine
Meningoencephalitis
Herpesviruses
Complete blood count
Cerebrospinal fluid
Diagnosis
Resumo:  Bovine herpesvirus 5 (BoHV-5) meningoencephalitis is one of the main causes of mortality by encephalopathy in Brazilian cattle herds. However, the neurological signs observed are common to several encephalopathies and do not contribute decisively to a diagnosis. In order to verify hematological and cerebrospinal fluid (CSF) changes, blood and CSF samples from naturally and experimentally infected bovines were evaluated. In natural cases (n=17), the samples were collected only once, and in experimental cases (n=7), the samples were sequentially obtained throughout disease progression. While routine methods were used to examine the samples, BoHV-5 infection was confirmed by a PCR assay. Blood analyses did not reveal any consistent hematological alterations and the leukogram results occasionally showed increases in leukocyte and segmented neutrophil. Hyperfibrinogenemia was noted in all experimentally infected calves and in half of the natural cases. Pleocytosis with mononuclear cells was a remarkable finding in CSF collected from both groups of animals and was present even in experimentally infected calves that remained asymptomatic. Therefore, CSF evaluation can be used as an auxiliary method in ante-mortem BoHV-5 diagnosis.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000700010
Editor:  Instituto de Tecnologia do Paraná - Tecpar
Relação:  10.1590/S1516-89132009000700010
Formato:  text/html
Fonte:  Brazilian Archives of Biology and Technology v.52 n.spe 2009
Direitos:  info:eu-repo/semantics/openAccess
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