| Registro completo |
| Provedor de dados: |
BABT
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| País: |
Brazil
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| Título: |
Green Tropical Phytoextracts - Promising Anticancer Alternative
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| Autores: |
Khan,Abid Ali
Omer,Kosar Ali
Talib,Ayesha
Ahmed,Haroon
Javed,Mohamad Arshad
Sarmidi,Roji Mohamad
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| Data: |
2016-01-01
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| Ano: |
2016
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| Palavras-chave: |
Labisia pumila
Ficus deltoidea
Anticancer Plant Extract
Prostate cancer.
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| Resumo: |
ABSTRACT The anticancer potential of aqueous extracts of tropical plants Ficus deltoidea and Labisia pumila were tested on human prostate carcinoma (DU145) cells. The effects of these extracts on the cells were observed through several tests such as cytotoxicity MTT assay, trypan blue exclusion assay (for cell viability), fluorescence and morphological observations. Both of the plant extracts had a growth repression effect on the cells with different concentrations. The best concentration (1x10-3 μg/mL) was chosen by determining their cytotoxic effects on human prostate cancer as well as fibroblast (normal) cells. The F. deltoidea extract showed more potency and killed the cells faster than L. pumila. Morphologically both extracts affected the cells in a similar way, i.e. the cells became irregular shaped, detached themselves and kept floating in the medium.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100328
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| Editor: |
Instituto de Tecnologia do Paraná - Tecpar
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| Relação: |
10.1590/1678-4324-2016160062
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| Formato: |
text/html
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| Fonte: |
Brazilian Archives of Biology and Technology v.59 2016
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| Direitos: |
info:eu-repo/semantics/openAccess
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