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Provedor de dados:  BABT
País:  Brazil
Título:  Anti-Quorum Sensing Potential of Antioxidant Quercetin and Resveratrol
Autores:  Erdönmez,Demet
Rad,Abbas Yousefi
Aksöz,Nilüfer
Data:  2018-01-01
Ano:  2018
Palavras-chave:  Anti-quorum sensing
Resveratrol
Quercetin
Antioxidant
Resumo:  ABSTRACT Quorum sensing system plays an active role in the regulation of pathogenicity of many microorganisms. Inhibition of pathogenicity or virulence factors will increase the success of treatment by preventing the development of antibiotic resistance. In this study, anti-quorum sensing activities of quercetin and resveratrol compounds, which have antioxidant property without damaging to host, have been determined via using biosensor bacteria: Chromobacterium violaceum ATCC 12472 and Chromobacterium violaceum CV026. As quorum sensing inhibitors, quercetin and resveratrol's cutting off the bacterial communication will prevent the treatment failures caused by the development of bacterial resistance. The development of layered drugs with antioxidant compounds such as quercetin and resveratrol will pave the way for new horizons for new therapeutic strategies.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100403
Editor:  Instituto de Tecnologia do Paraná - Tecpar
Relação:  10.1590/1678-4324-2017160756
Formato:  text/html
Fonte:  Brazilian Archives of Biology and Technology v.61 2018
Direitos:  info:eu-repo/semantics/openAccess
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