| Registro completo |
| Provedor de dados: |
BABT
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| País: |
Brazil
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| Título: |
Extracts of red yolk from duck eggs inhibit metastasis of human mammary carcinoma (4T1) cells in mice
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| Autores: |
Qi-bin,Song
Yi,Yao
Wei-guo,Hu
Sheng-hua,Zhang
Xiao-wei,Yan
Rui,Yang
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| Data: |
2011-06-01
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| Ano: |
2011
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| Palavras-chave: |
Duck egg yolk
Extracts
Mammary carcinoma
Metastasis
4T1 Cells
BALB/c mice
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| Resumo: |
The aim of the present study was to investigate the in vivo anti-metastatic activity of the red pigments of red yolk eggs laid by the ducks dieting on Potamogeton cripus L on the mammary carcinoma (4T1). The pigments were extracted with petroleum ether and acetone (2:1, v/v). BALB/c mice were divided into three groups (n=6), fed with the extracts at 150 mg/kg body weight (BW)/day (DEYE-H) or at 50 mg/kg BW/day (DEYE-L) and identical buffer without the extract (control group). The extracts were administered for 34 days. The treatment significantly inhibited the growth of orthotopical 4T1 tumour (DEYE-H vs control, 1:2; DEYE-L vs control, 2:3) and reduced the metastasis of tumour in the lungs (DEYE-H vs control, 4:7; DEYE-L vs control, 5:7), without statistical difference of body weight among the three groups.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000300011
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| Editor: |
Instituto de Tecnologia do Paraná - Tecpar
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| Relação: |
10.1590/S1516-89132011000300011
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| Formato: |
text/html
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| Fonte: |
Brazilian Archives of Biology and Technology v.54 n.3 2011
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| Direitos: |
info:eu-repo/semantics/openAccess
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