| Registro completo |
| Provedor de dados: |
BJID
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| País: |
Brazil
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| Título: |
Adherence to antiretroviral therapy of Brazilian HIV-infected children and their caregivers
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| Autores: |
Ricci,Gabriela
Netto,Eduardo Martins
Luz,Estela
Rodamilans,Cynthia
Brites,Carlos
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| Data: |
2016-10-01
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| Ano: |
2016
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| Palavras-chave: |
Adherence
Antiretroviral therapy
Children
Caregivers
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| Resumo: |
Abstract Background Successful treatment of HIV-positive children requires a high level of adherence (at least 95%) to highly active antiretroviral therapy. Adherence is influenced by factors related to the child and caregivers. Objectives To evaluate children and caregivers characteristics associated to children's adherence. Methods Cross-sectional study, from September 2013 to June 2015, comprising a sample of caregivers of perinatally HIV-infected children, in the age group of 1–12 years, under antiretroviral therapy for at least 6 months and on follow-up in two AIDS reference centers in Salvador, Bahia. Caregiver self-reports were the sole source of 4 days adherence and sociodemographic information. Study participants who reported an intake >95% of prescribed medication were considered adherents. A variable, (“Composed Adherence”), was created to better evaluate adherence. Results We included 77 children and their caregivers. 88.3% of the caregivers were female, the median age was 38.0 years (IQR 33.5–47.5), 48.1% were white or mixed, 72.7% lived in Salvador and 53.2% had no fixed income. The 4 days child's adherence was associated only to caregivers that received less than a minimum salary (p < 0.05), 70.1% of the caregivers had less than four years of formal education, 81.8% were children's relative and 53.2% of the caregivers were HIV positive. The caregiver's pharmacy refill, long-term adherence and 4 days adherence, were significantly associated with composed adherence (p < 0.05). Child's long-term adherence was strongly associated to the 4 days child's adherence referred by caregiver (p < 0.001). Conclusions Our results suggest the need of improvement in HIV-infected children adherence, through reinforcement of the caregivers own adherence.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000500429
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| Editor: |
Brazilian Society of Infectious Diseases
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| Relação: |
10.1016/j.bjid.2016.05.009
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Infectious Diseases v.20 n.5 2016
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| Direitos: |
info:eu-repo/semantics/openAccess
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