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Provedor de dados:  BJID
País:  Brazil
Título:  Risk factors for laboratory-confirmed bloodstream infection in neonates undergoing surgical procedures
Autores:  Romanelli,Roberta Maia de Castro
Anchieta,Lêni Márcia
Carvalho,Elaine Alvarenga de Almeida
Silva,Lorena Ferreira da Glória e
Nunes,Rafael Viana Pessoa
Mourão,Paulo Henrique
Clemente,Wanessa Trindade
Bouzada,Maria Cândida Ferrarez
Data:  2014-08-01
Ano:  2014
Palavras-chave:  Newborn intensive care units
Infection control
Surgery
Sepsis
Resumo:  BACKGROUND: Healthcare Associated Infections constitute an important problem in Neonatal Units and invasive devices are frequently involved. However, studies on risk factors of newborns who undergo surgical procedures are scarce. OBJECTIVE: To identify risk factors for laboratory-confirmed bloodstream infection in neonates undergoing surgical procedures. METHODS: This case-control study was conducted from January 2008 to May 2011, in a referral center. Cases were of 21 newborns who underwent surgery and presented the first episode of laboratory-confirmed bloodstream infection. Control was 42 newborns who underwent surgical procedures without notification of laboratory-confirmed bloodstream infection in the study period. Information was obtained from the database of the Hospital Infection Control Committee Notification of infections and related clinical data of patients that routinely collected by trained professionals and follow the recommendations of Agência Nacional de Vigilância Sanitária and analyzed with Statistical Package for Social Sciences. RESULTS: During the study period, 1141 patients were admitted to Neonatal Unit and 582 Healthcare Associated Infections were reported (incidence-density of 25.75 Healthcare Associated Infections/patient-days). In the comparative analysis, a higher proportion of laboratory-confirmed bloodstream infection was observed in preterm infants undergoing surgery (p = 0.03) and use of non-invasive ventilation was a protective factor (p = 0.048). Statistically significant difference was also observed for mechanical ventilation duration (p = 0.004), duration of non-invasive ventilation (p = 0.04), and parenteral nutrition duration (p = 0.003). In multivariate analysis duration of parenteral nutrition remained significantly associated with laboratory-confirmed bloodstream infection (p = 0.041). CONCLUSIONS: Shortening time on parenteral nutrition whenever possible and preference for non-invasive ventilation in neonates undergoing surgery should be considered in the assistance of these patients, with the goal of reducing Healthcare Associated Infections, especially laboratory-confirmed bloodstream infection.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000400400
Editor:  Brazilian Society of Infectious Diseases
Relação:  10.1016/j.bjid.2013.12.003
Formato:  text/html
Fonte:  Brazilian Journal of Infectious Diseases v.18 n.4 2014
Direitos:  info:eu-repo/semantics/openAccess
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