Registro completo |
Provedor de dados: |
BJID
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País: |
Brazil
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Título: |
Human Papillomavirus prevalence, viral load and cervical intraepithelial neoplasia in HIV-infected women
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Autores: |
Levi,José E.
Fink,Maria C.S.
Canto,Cynthia L.M.
Carretiero,Nadily
Matsubara,Regina
Linhares,Iara
Dores,Gérson B. das
Castelo,Adauto
Segurado,Aluísio
Uip,David E.
Eluf Neto,José
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Data: |
2002-06-01
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Ano: |
2002
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Palavras-chave: |
Human Papillomavirus
Cervical intraepithelial neoplasia
HIV-infected women
Viral load
AIDS
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Resumo: |
HIV-infected women from São Paulo city were enrolled in a cross-sectional study on Human Papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN) prevalence and their association with laboratory markers of AIDS, namely HIV viral load and CD4+ cell counts. A cervical specimen was collected and submitted to Hybrid Capture, a test for HPV viral load determination. HPV-DNA was detected in 173 of 265 women (64.5%). Twenty (7.5%) women were infected by one or more low-risk viruses, 89 (33%) by one or more high-risk viruses, and 64 (24%) harbored at least one HPV type from each risk group. Abnormal smears were observed in 19% of the patients, though there were no invasive carcinomas. Severely immunosuppressed patients (CD4/µL <100) were at the greatest risk of having a cytological abnormality and a high high-risk HPV viral load.
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Tipo: |
Info:eu-repo/semantics/article
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Idioma: |
Inglês
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Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000300005
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Editor: |
Brazilian Society of Infectious Diseases
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Relação: |
10.1590/S1413-86702002000300005
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Formato: |
text/html
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Fonte: |
Brazilian Journal of Infectious Diseases v.6 n.3 2002
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Direitos: |
info:eu-repo/semantics/openAccess
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