| Registro completo |
| Provedor de dados: |
BJID
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| País: |
Brazil
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| Título: |
Western blot seroindeterminate individuals for Human T-lymphotropic Virus 1/2 (HTLV-1/2) in Fortaleza (Brazil): a serological and molecular diagnostic and epidemiological approach
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| Autores: |
Santos,Terezinha de Jesus Teixeira
Costa,Carlos Maurício de Castro
Goubau,Patrick
Vandamme,Anne-Mieke
Desmyter,Jan
Van Dooren,Sonia
Mota,Rosa M. S.
Costa,Francine Bovy de Castro
Oliveira,Ana C. S.
Gomes,Vânia Barreto A.F.
Carneiro-Proietti,Anna B.
Bruin,Veralice Meireles Sales de
Sousa,Francisca C. F. de
Oriá,Reinaldo Barreto
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| Data: |
2003-06-01
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| Ano: |
2003
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| Palavras-chave: |
Epidemiology
PCR
HTLV-1/2
Seroindeterminate individuals
Hepatitis
Syphilis
Blood transfusion
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| Resumo: |
How to handle Western blot (WB) seroindeterminate individuals for Human T-lymphotropic Virus 1/2 (HTLV-1/2) constitutes a challenge for blood banks and fam ilies. We made a cross-sectional study of 191 enzyme linked immunoassay (EIA) reactive individuals from the hematological center (HEMOCE) of Fortaleza (Brazil), examining their serological (WB) and molecular (PCR) diagnosis, and demographic profiles, as well as a possible association of their condition with other infectious pathologies and risk factors. Ethical institutional approval and personal consent were obtained. Out of 191 EIA reactive individuals, 118 were WB seroindeterminate and 73 were seropositive for HTLV-1/2. In the PCR analysis of 41 WB seroindeterminate individuals, 9 (22%) were positive and 32 (78%) were negative for HTLV-1/2. The demographic analysis indicated a trend towards a predominance of males among the seroindeterminate individuals and females in the seropositive ones. The seroindeterminate individuals were younger than the seropositive ones. We did not find any association of these conditions with syphilis, Chagas disease or HIV or hepatitis, and with risk factors such as breast-feeding, blood transfusion, STD (syphilis) and IDU.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000300005
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| Editor: |
Brazilian Society of Infectious Diseases
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| Relação: |
10.1590/S1413-86702003000300005
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Infectious Diseases v.7 n.3 2003
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| Direitos: |
info:eu-repo/semantics/openAccess
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