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Provedor de dados:  BJID
País:  Brazil
Título:  Prevalence of lipodystrophy and risk factors for dyslipidemia in HIV-infected children in Brazil
Autores:  Papi,Luanda
Menezes,Ana Carolina G.B.
Rocha,Hélio
Abreu,Thalita F.
Oliveira,Ricardo Hugo de
Frota,Ana Cristina C.
Evangelista,Lucia de A.
Hofer,Cristina B.
Data:  2014-08-01
Ano:  2014
Palavras-chave:  HIV
Lipodystrophy
Dyslipidemia
Children
Resumo:  The aim of present study was to describe the frequency of lipodystrophy syndrome associated with HIV (LSHIV) and factors associated with dyslipidemia in Brazilian HIV infected children. HIV infected children on antiretroviral treatment were evaluated (nutritional assessment, physical examination, and laboratory tests) in this cross-sectional study. Univariate analysis was performed using Mann-Whitney test or Fisher's exact test followed by logistic regression analysis. Presence of dyslipidemia (fasting cholesterol >200 mg/dl or triglycerides >130 mg/dl) was the dependent variable. 90 children were enrolled. The mean age was 10.6 years (3-16 years), and 52 (58%) were female. LSHIV was detected in 46 children (51%). Factors independently associated with dyslipidemia were: low intake of vegetables/fruits (OR = 3.47, 95%CI = 1.04-11.55), current use of lopinavir/ritonavir (OR = 2.91, 95%CI = 1.11-7.67). In conclusion, LSHIV was frequently observed; inadequate dietary intake of sugars and fats, as well as current use of lopinavir/ritonavir was associated with dyslipidemia.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000400394
Editor:  Brazilian Society of Infectious Diseases
Relação:  10.1016/j.bjid.2013.12.007
Formato:  text/html
Fonte:  Brazilian Journal of Infectious Diseases v.18 n.4 2014
Direitos:  info:eu-repo/semantics/openAccess
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