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Provedor de dados:  BJID
País:  Brazil
Título:  Characterization of rickettsia rickettsii in a case of Fatal Brazilian spotted fever in the city of Rio de Janeiro, Brazil
Autores:  Lamas,Cristiane
Favacho,Alexsandra
Rozental,Tatiana
Bóia,Márcio N.
Kirsten,Andrei H.
Guterres,Alexandro
Barreira,Jairo
Lemos,Elba Regina S. de
Data:  2008-04-01
Ano:  2008
Palavras-chave:  Brazilian spotted fever
Spotted fever group rickettsia
Rickettsia rickettsii
Lethal case
Rio de Janeiro city
Indirect immunofluorescence
Polymerase chain reaction
Central nervous system involvement
Resumo:  A lethal case of Brazilian spotted fever (BSF) is presented. Clinical features were initially of gastrointestinal involvement and evolved with progression to septic shock, meningoencephalitis and death on the 6th day of illness. Indirect immunofluorescence assay (IFA) for spotted fever group rickettsia (SFGR) was non-reactive. Diagnosis was confirmed by the polymerase chain reaction (PCR) and the nucleotide sequencing of a fragment of the ompA gene showed 100% homology to Rickettsia rickettsii. BSF has not been reported in the city of Rio de Janeiro in the last three decades, and the present description should alert the clinicians to its presence in urban Rio de Janeiro, and to the differential diagnosis with dengue fever, gastroenteritis, leptospirosis and bacterial septic shock, among others.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000200010
Editor:  Brazilian Society of Infectious Diseases
Relação:  10.1590/S1413-86702008000200010
Formato:  text/html
Fonte:  Brazilian Journal of Infectious Diseases v.12 n.2 2008
Direitos:  info:eu-repo/semantics/openAccess
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