| Registro completo |
| Provedor de dados: |
55
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| País: |
Brazil
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| Título: |
Elevated serum CA 19-9 levels in patients with pulmonary nontuberculous mycobacterial disease
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| Autores: |
Hong,Ji Young
Jang,Sun Hee
Kim,Song Yee
Chung,Kyung Soo
Song,Joo Han
Park,Moo Suk
Kim,Young Sam
Kim,Se Kyu
Chang,Joon
Kang,Young Ae
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| Data: |
2016-02-01
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| Ano: |
2016
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| Palavras-chave: |
Carbohydrate antigen 19-9
Nontuberculous mycobacteria
Tuberculosis
Biological marker
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| Resumo: |
Abstract Increased serum CA 19-9 levels in patients with nonmalignant diseases have been investigated in previous reports. This study evaluates the clinical significance of serum CA 19-9 elevation in pulmonary nontuberculous mycobacterial disease and pulmonary tuberculosis. The median CA 19-9 level was higher in patients with pulmonary nontuberculous mycobacterial disease than in patients with pulmonary tuberculosis (pulmonary nontuberculous mycobacterial disease: 13.80, tuberculosis: 5.85, p < 0.001). A multivariate logistic regression analysis performed in this study showed that Mycobacterium abscessus (OR 9.97, 95% CI: 1.58, 62.80; p = 0.014) and active phase of pulmonary nontuberculous mycobacterial disease (OR 12.18, 95% CI: 1.07, 138.36, p = 0.044) were found to be risk factors for serum CA 19-9 elevation in pulmonary nontuberculous mycobacterial disease. The serum CA 19-9 levels showed a tendency to decrease during successful treatment of pulmonary nontuberculous mycobacterial disease but not in pulmonary tuberculosis. These findings suggest that CA 19-9 may be a useful marker for monitoring therapeutic responses in pulmonary nontuberculous mycobacterial disease, although it is not pulmonary nontuberculous mycobacterial disease-specific marker.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000100026
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| Editor: |
Brazilian Society of Infectious Diseases
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| Relação: |
10.1016/j.bjid.2015.09.005
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Infectious Diseases v.20 n.1 2016
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| Direitos: |
info:eu-repo/semantics/openAccess
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