| Registro completo |
| Provedor de dados: |
BJID
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| País: |
Brazil
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| Título: |
Occult B infection in the Brazilian northeastern region: a preliminary report
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| Autores: |
Almeida,Delvone
Tavares-Neto,José
Trepo,Christian
Almeida,Alessandro
Mello,Caroline
Chemin,Isabelle
Paraná,Raymundo
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| Data: |
2008-08-01
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| Ano: |
2008
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| Palavras-chave: |
Anti-HBc alone
Hepatitis B virus
Occult hepatitis B
Ultrasensitive PCR
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| Resumo: |
A sentinel study on viral hepatitis is currently being carried out in the village of Cavunge in a semiarid rural region of the state of Bahia, northeastern Brazil. This study has identified individuals in whom anti-HBc IgG was the only serological marker for hepatitis B virus (HBV). This serological pattern may constitute evidence of occult HBV infection. This study Investigated the possibility of occult hepatitis B virus infection in individuals in a rural community who tested positive for anti-HBc IgG alone. A cross-sectional population-based study. ELISA III was performed on serum samples to test for serological viral markers, and ultrasensitive PCR (US-PCR) was used to assess viremia. Among the 1,536 serum samples, 3.6% (n=55) were positive for anti-HBc alone. Four years after this first serological survey, 31 of those 55 individuals (56.3%) were retested, and 11 (35.5%) remained anti-HBc positive alone. Two of these 31 (6.5%) were HBV-DNA positive based on US-PCR, with normal aminotransferase levels in both cases. Cases of occult hepatitis B infection were identified in this semiarid rural community of northeastern Brazil, where endemicity of HBV is moderate.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000400010
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| Editor: |
Brazilian Society of Infectious Diseases
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| Relação: |
10.1590/S1413-86702008000400010
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Infectious Diseases v.12 n.4 2008
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| Direitos: |
info:eu-repo/semantics/openAccess
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