| Registro completo |
| Provedor de dados: |
BJID
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| País: |
Brazil
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| Título: |
Hepatitis C as a risk factor for diabetes type 2: lack of evidence in a hospital in central-west Brazil
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| Autores: |
Costa,Luce Marina Freires Corrêa da
Mussi,Aparecida Duarte Hg
Brianeze,Marylina Rodrigues
Souto,Francisco José Dutra
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| Data: |
2008-02-01
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| Ano: |
2008
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| Palavras-chave: |
Type 2 diabetes mellitus
Case control study
Risk factors
Hepatitis C virus
Epidemiology
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| Resumo: |
In order to assess the importance of HCV infection as a possible risk factor for type 2 diabetes mellitus, a case-control study was conducted, comparing the prevalence of HCV infection among diabetic and non-diabetic patients. Diabetic outpatients attending to a University Hospital in Central-West Brazil were evaluated between April and October 2005. A control group composed by patients from the same institution was matched by gender and age. Candidates to control group were included only if fasting glucose measures were under 100 mg/dL. Diabetics and controls had blood samples taken in order to test for antibodies against HCV (anti-HCV) by enzyme-immunoassay. Polymerase chain reaction and immunoblot were performed to confirm the anti-HCV status. Each group included 206 participants. Despite of the groups were in general comparable. The diabetics had a greater body mass average and smaller family income. The prevalence of confirmed anti-HCV in the diabetic group was of 1.4%, which was similar to the controls (1%). Finding statistical difference may have been hampered by the low frequency of HCV infection in both groups. It was not possible to demonstrate a role of HCV as an etiologic factor in type 2 diabetes, since HCV infected patients represented a small portion of the overall diabetes cases. This finding does not allow to recommend regular screening for HCV infection in type 2 diabetics in this region.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000100007
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| Editor: |
Brazilian Society of Infectious Diseases
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| Relação: |
10.1590/S1413-86702008000100007
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Infectious Diseases v.12 n.1 2008
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| Direitos: |
info:eu-repo/semantics/openAccess
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