| Registro completo |
| Provedor de dados: |
BJID
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| País: |
Brazil
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| Título: |
The influenza season 2016/17 in Bucharest, Romania – surveillance data and clinical characteristics of patients with influenza-like illness admitted to a tertiary infectious diseases hospital
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| Autores: |
Drăgănescu,Anca
Săndulescu,Oana
Florea,Dragoş
Vlaicu,Ovidiu
Streinu-Cercel,Anca
Oţelea,Dan
Aramă,Victoria
Luminos,Monica Luminiţa
Streinu-Cercel,Adrian
Niţescu,Maria
Ivanciuc,Alina
Bacruban,Rodica
Piţigoi,Daniela
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| Data: |
2018-10-01
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| Ano: |
2018
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| Palavras-chave: |
A/H3
B/Victoria
ILI
Influenza
SARI
Subtype
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| Resumo: |
ABSTRACT Background: Influenza continues to drive seasonal morbidity, particularly in settings with low vaccine coverage. Objectives: To describe the influenza cases and viral circulation among hospitalized patients. Methods: A prospective study based on active surveillance of inpatients with influenza-like illness from a tertiary hospital in Bucharest, Romania, in the season 2016/17. Results: A total of 446 patients were tested, with a balanced gender distribution. Overall, 192 (43%) patients tested positive for influenza, with the highest positivity rate in the age groups 3–13 years and >65 years. Peak activity occurred between weeks 1 and 16/2017, with biphasic distribution: A viruses were replaced by B viruses from week 9/2017; B viruses predominated (66.1%). Among the 133 (69.3%) subtyped samples, all influenza A were subtype H3 (n = 57) and all influenza B were B/Victoria (n = 76). Patients who tested positive for influenza presented fewer comorbidities (p = 0.012), except for the elderly, in whom influenza was more common in patients with comorbidities (p = 0.050). Disease evolution was generally favorable under antiviral treatment. The length of hospital stay was slightly longer in patients with influenza-like illness who tested patients negative for influenza (p = 0.031). Conclusions: Distinctive co-circulation of A/H3 and B/Victoria in Bucharest, Romania in the 2016/17 influenza season was found. While the A/H3 subtype was predominant throughout Europe that season, B/Victoria appears to have circulated specifically in Romania and the Eastern European region, predominantly affecting preschoolers and school children.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000500377
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| Editor: |
Brazilian Society of Infectious Diseases
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| Relação: |
10.1016/j.bjid.2018.10.275
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Infectious Diseases v.22 n.5 2018
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| Direitos: |
info:eu-repo/semantics/openAccess
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