| Registro completo |
| Provedor de dados: |
BJID
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| País: |
Brazil
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| Título: |
The impact of dengue on liver function as evaluated by aminotransferase levels
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| Autores: |
Souza,Luiz José de
Nogueira,Rita Maria Ribeiro
Soares,Leandro Cordeiro
Soares,Carlos Eduardo Cordeiro
Ribas,Bruno Fernandes
Alves,Felipe Pinto
Vieira,Fabíola Rodrigues
Pessanha,Felipe Eulálio Baldi
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| Data: |
2007-08-01
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| Ano: |
2007
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| Palavras-chave: |
Dengue
Dengue hemorrhagic fever
Aminotransferases
Hepatitis
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| Resumo: |
The objective of this study was to evaluate the impact of dengue virus infection on liver function by measuring aminotransferase in blood samples from patients serologically diagnosed by according to two MAC-ELISA protocols. Degrees of liver damage were classified according to aminotransferase levels: grade A - normal enzyme levels; grade B - increased levels of at least one of the enzymes; grade C - increased, with at least one of the enzymes being at levels higher than three times the upper reference values; grade D - acute hepatitis, with aminotransferase levels at least ten times their normal values. Of the 169 serologically confirmed cases of dengue at the dengue referral center in Campos dos Goytacazes in the state of Rio de Janeiro, Brazil, 65.1% had abnormal aminotransferase levels: 81 cases being classified as grade B, 25 as grade C and 3 as grade D. A further 34.9% of cases had normal enzyme levels and were classified as grade A. Liver damage is a common complication of dengue infection and aminotransferase levels are a valuable marker for monitoring these cases.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000400007
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| Editor: |
Brazilian Society of Infectious Diseases
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| Relação: |
10.1590/S1413-86702007000400007
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Infectious Diseases v.11 n.4 2007
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| Direitos: |
info:eu-repo/semantics/openAccess
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