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Provedor de dados:  BJID
País:  Brazil
Título:  Parainfluenza virus as a cause of acute respiratory infection in hospitalized childrens
Autores:  Pecchini,Rogério
Berezin,Eitan Naaman
Souza,Maria Cândida
Vaz-de-Lima,Lourdes de Andrade
Sato,Neuza
Salgado,Maristela
Ueda,Mirthes
Passos,Saulo Duarte
Rangel,Raphael
Catebelota,Ana
Data:  2015-08-01
Ano:  2015
Palavras-chave:  Parainfluenza
Paramyxoviridae infections
Respiratory tract infections
Respiratory virus
Resumo:  Background: Human parainfluenza viruses account for a significant proportion of lower respiratory tract infections in children.Objective: To assess the prevalence of Human parainfluenza viruses as a cause of acute respiratory infection and to compare clinical data for this infection against those of the human respiratory syncytial virus.Methods: A prospective study in children younger than five years with acute respiratory infection was conducted. Detection of respiratory viruses in nasopharyngeal aspirate samples was performed using the indirect immunofluorescence reaction. Length of hospital stay, age, clinical history and physical exam, clinical diagnoses, and evolution (admission to Intensive Care Unit or general ward, discharge or death) were assessed. Past personal (premature birth and cardiopathy) as well as family (smoking and atopy) medical factors were also assessed.Results: A total of 585 patients were included with a median age of 7.9 months and median hospital stay of six days. No difference between the HRSV+ and HPIV+ groups was found in terms of age, gender or length of hospital stay. The HRSV+ group had more fever and cough. Need for admission to the Intensive Care Unit was similar for both groups but more deaths were recorded in the HPIV+ group. The occurrence of parainfluenza peaked during the autumn in the first two years of the study.Conclusion: Parainfluenza was responsible for significant morbidity, proving to be the second-most prevalent viral agent in this population after respiratory syncytial virus. No difference in clinical presentation was found between the two groups, but mortality was higher in the HPIV+ group.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000400358
Editor:  Brazilian Society of Infectious Diseases
Relação:  10.1016/j.bjid.2015.03.002
Formato:  text/html
Fonte:  Brazilian Journal of Infectious Diseases v.19 n.4 2015
Direitos:  info:eu-repo/semantics/openAccess
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