| Registro completo |
| Provedor de dados: |
BJID
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| País: |
Brazil
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| Título: |
Perinatal morbidity and mortality associated with chlamydial infection: a meta-analysis study
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| Autores: |
Silva,Maria José Penna Maisonnette de Attayde
Florêncio,Gilzandra Lira Dantas
Gabiatti,José Roberto Erbolato
Amaral,Rose Luce do
Eleutério Júnior,José
Gonçalves,Ana Katherine da Silveira
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| Data: |
2011-12-01
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| Ano: |
2011
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| Palavras-chave: |
Chlamydia trachomatis
Perinatal mortality
Morbidity
Meta-analysis
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| Resumo: |
OBJECTIVE: To evaluate the effect of Chlamydia trachomatis infection during pregnancy on perinatal morbidity and mortality. METHODS: Systematic review and meta-analysis in an electronic database and manual, combining high sensitivity specific descriptors seeking to answer the research objective. The articles considered to be of high methodological quality (score above 6 on the Newcastle-Ottawa Scale) were assessed by meta-analysis. RESULTS: Summary estimates of 12 studies were calculated by means of Mantel-Haenszel test with 95% confidence interval. It was observed that Chlamydia infection during pregnancy increased risk of preterm labor (relative risk (RR) = 1.35 [1.11, 1.63]), low birth weight (RR = 1.52 [1.24, 1.87]) and perinatal mortality (RR = 1.84 [1.15, 2.94]). No evidence of increased risk was associated with Chlamydia infection in regard to premature rupture of membranes (RR = 1.13 [0.95, 1.34]), abortion and postpartum endometritis (RR = 1.20 [0.65, 2.20] and 0.89 [0.49, 1.61] respectively). CONCLUSION: The diagnosis and treatment of Chlamydia cervicitis during pregnancy can reduce perinatal morbidity and mortality associated with this infection. However, clinical trials are needed to confirm these findings.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000600006
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| Editor: |
Brazilian Society of Infectious Diseases
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| Relação: |
10.1590/S1413-86702011000600006
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Infectious Diseases v.15 n.6 2011
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| Direitos: |
info:eu-repo/semantics/openAccess
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