| Registro completo |
| Provedor de dados: |
BJID
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| País: |
Brazil
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| Título: |
Chronic skull osteomyelitis due to Cryptococcus neoformans: first case report in an HIV-infected patient
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| Autores: |
Adiwardana,Natanael Sutikno
Morás,Juliana de Angelo
Bernardo,Leandro Lombo
Klautau,Giselle Burlamaqui
Queiroz,Wladimir
Vidal,Jose Ernesto
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| Data: |
2018-11-01
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| Ano: |
2018
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| Palavras-chave: |
Cryptococcus neoformans
Osteomyelitis
Skull
HIV
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| Resumo: |
ABSTRACT Osteomyelitis due to Cryptococcus neoformans are described in mostly 10% of patients with disseminated cryptococcosis, being direct inoculation even more uncommon. We report the case of an HIV-infected patient with history of recurring itching on his scalp and repetitive local trauma. For eighteen months, he noticed a painful and slow growing lump on his scalp. He was submitted to an excisional biopsy of the lesion but no etiological diagnosis was identified. After this procedure, the post-surgical wound never completely healed. At admission, the patient presented nausea and headache for three days and an open orifice into his skull. Investigations confirmed meningitis and skull osteomyelitis caused by Cryptococcus neoformans. He was treated with bone debridement and combined systemic antifungals, showing good clinical and laboratorial outcome. Cryptococcal disease should be included in the differential diagnoses of chronic osteomyelitis in HIV-infected patients and trauma is a possible source of infection.
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| Tipo: |
Info:eu-repo/semantics/report
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000600499
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| Editor: |
Brazilian Society of Infectious Diseases
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| Relação: |
10.1016/j.bjid.2018.11.004
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Infectious Diseases v.22 n.6 2018
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| Direitos: |
info:eu-repo/semantics/openAccess
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