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Provedor de dados:  BJID
País:  Brazil
Título:  Toxoplasma gondii infection in pregnancy
Autores:  Lopes,Fabiana Maria Ruiz
Gonçalves,Daniela Dib
Mitsuka-Breganó,Regina
Freire,Roberta Lemos
Navarro,Italmar Teodorico
Data:  2007-10-01
Ano:  2007
Palavras-chave:  Toxoplasmosis
Toxoplasma gondii
Congenital transmission
Pregnant women
Resumo:  Toxoplasmosis is caused by an intracellular protozoan, Toxoplasma gondii, which has a wide geographical distribution. The main infection routes are ingestion of cysts from raw or badly-cooked meat, ingestion of oocysts from substrates contaminated with the feces of infected felines and congenital transmission by tachyzoites. The congenital form results in a severe systemic disease, because if the mother is infected for the first time during gestation, she can present a temporary parasitemia that will infect the fetus. Many of the clinical symptoms are seen in congenitally-infected children, from a mild disease to serious signs, such as mental retardation. Early diagnosis during the pregnancy is highly desirable, allowing prompt intervention in cases of infection, through treatment of pregnant women, reducing the probability of fetal infection and consequent substantial damage to the fetus. Conventional tests for establishment of a fetal diagnosis of toxoplasmosis include options from serology to PCR. Prevention of human toxoplasmosis is based on care to avoid infection, understanding the disease and serological exams during gestation. Pregnant women should be tested serologically from three months gestation, until one month after childbirth. Inclusion of serology for congenital toxoplasmosis along with the basic Guthrie test for PKU is of fundamental importance for early diagnosis of infection and so that treatment is initiated, in order to avoid possible sequels in the infant.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000500011
Editor:  Brazilian Society of Infectious Diseases
Relação:  10.1590/S1413-86702007000500011
Formato:  text/html
Fonte:  Brazilian Journal of Infectious Diseases v.11 n.5 2007
Direitos:  info:eu-repo/semantics/openAccess
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