| Registro completo |
| Provedor de dados: |
BJID
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| País: |
Brazil
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| Título: |
Molecular diversity of human parvovirus B19 during two outbreaks of erythema infectiosum in Brazil
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| Autores: |
Garcia,Rita de Cássia Nasser Cubel
Pereira,Renata Freire Alves
Azevedo,Kátia Martins Lopes de
Castro,Tatiana Xavier de
Mello,Francisco C.A.
Setubal,Sérgio
Siqueira,Marilda M.
Brown,David
Oliveira,Solange Artimos de
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| Data: |
2017-02-01
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| Ano: |
2017
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| Palavras-chave: |
B19V genotypes
Outbreak
Erythema infectiosum
Brazil
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| Resumo: |
Abstract This study was conducted to provide information on the genetic diversity of human parvovirus B19 (B19V) circulating in the municipality of Niterói, Rio de Janeiro, Southeast Brazil during 1996–2006, a period with two distinct outbreaks of B19V infection: 1999–2000 and 2004–2005. A total of 27 sera from patients with erythema infectiosum and five sera from HIV-infected patients that tested positive for B19V DNA during the study period were analyzed. To genotype B19V strains, a semi-nested PCR for partial amplification of the capsid gene was performed and sequence analysis revealed that 31 sequences belonged to subgenotype 1a (G1a) of the main genotype 1 and one sequence was characterized as subgenotype 3b (G3b). The phylogenetic tree supported the division of the G1a into two well-defined clades with 1.3% of divergence. The low diversity of the G1a strains may be explained by the fact that all patients had acute B19V infection and 30/32 sera were collected during two distinct outbreaks. The G3b strain was from an HIV-infected patient who seroconverted to anti-B19 IgG antibodies in September/2005. This is the first report of G3b in the state of Rio de Janeiro.
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| Tipo: |
Info:eu-repo/semantics/other
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000100102
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| Editor: |
Brazilian Society of Infectious Diseases
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| Relação: |
10.1016/j.bjid.2016.11.002
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Infectious Diseases v.21 n.1 2017
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| Direitos: |
info:eu-repo/semantics/openAccess
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