| Registro completo |
| Provedor de dados: |
BJID
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| País: |
Brazil
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| Título: |
Epidemiological and microbiological analysis of ventilator-associated pneumonia patients in a public teaching hospital
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| Autores: |
Silva Júnior,João Manoel da
Rezende,Ederlon
Guimarães,Thaís
Campos,Edvaldo V. dos
Magno,Luiz André
Consorti,Lívia
Pereira,Renata Andréa Pietro
Nascimento,Maria de Lourdes
Mendonça,João Silva de
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| Data: |
2007-10-01
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| Ano: |
2007
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| Palavras-chave: |
Ventilator-associated pneumonia
Epidemiology
Microbiology
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| Resumo: |
Ventilator-associated pneumonia (VAP) is the most commonly-acquired infection in patients in intensive care units. We analyzed epidemiological and microbiological characteristics and the outcome, in a cohort of critically-ill patients with confirmed diagnosis of VAP. All patients who had been on mechanical ventilation (MV) for more than 48 hours were included in our study; material collection for microbiological analysis was done within the first 24 hours after beginning treatment or after changing antibiotics. There were 55/265 (20.7%) VAP cases diagnosed, at a rate of 21.6 episodes per 1,000 days of mechanical ventilation. Mean age of the patients was 66 years, with a mean APACHE II score of 26.7 + 7.0; male patients were more prevalent. The mortality rates in the intensive care unit (ICU) and during the hospital stay were 71% and 80%, respectively. MV duration in patients with VAP was 17 (range 3-43) days and among patients who had not developed VAP, 6 (2-32) days (p < 0.0001). 98.2% of the samples were positive, with a high prevalence of Gram-negative bacteria, mainly Acinetobacter calcoaceticus. Risk factors for death included age, MV duration and surgery. VAP incidence in this sample of critically-ill patients was high, with a high mortality rate. Control and prevention strategies based on continuing education of healthcare workers, developed by a multidisciplinary team, should be encouraged to minimize morbimortality of this infection.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000500009
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| Editor: |
Brazilian Society of Infectious Diseases
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| Relação: |
10.1590/S1413-86702007000500009
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Infectious Diseases v.11 n.5 2007
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| Direitos: |
info:eu-repo/semantics/openAccess
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