| Registro completo |
| Provedor de dados: |
BJID
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| País: |
Brazil
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| Título: |
To evaluate of the effect of adding licorice to the standard treatment regimen of Helicobacter pylori
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| Autores: |
Hajiaghamohammadi,Ali Akbar
Zargar,Ali
Oveisi,Sonia
Samimi,Rasoul
Reisian,Sedigheh
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| Data: |
2016-12-01
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| Ano: |
2016
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| Palavras-chave: |
Helicobacter pylori
Licorice
Dyspepsia
Peptic ulcer
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| Resumo: |
ABSTRACT Objective: The aim of this study was to evaluate the effect of licorice in H. pylori eradication in patients suffering from dyspepsia either with peptic ulcer disease (PUD) or non-ulcer dyspepsia (NUD) in comparison to the clarithromycin-based standard triple regimen. Methods: In this randomized controlled clinical trial, 120 patients who had positive rapid urease test were included and assigned to two treatment groups: control group that received a clarithromycin-based triple regimen, and study group that received licorice in addition to the clarithromycin-based regimen for two weeks. H. pylori eradication was assessed six weeks after therapy. Data was analyzed by chi-square and t-test with SPSS 16 software. Results: Mean ages and SD were 38.8 ± 10.9 and 40.1 ± 10.4 for the study and control groups, respectively, statistically similar. Peptic ulcer was found in 30% of both groups. Response to treatment was 83.3% and 62.5% in the study and control groups, respectively. This difference was statistically significant. Conclusion: Addition of licorice to the triple clarithromycin-based regimen increases H. pylori eradication, especially in the presence of peptic ulcer disease.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000600534
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| Editor: |
Brazilian Society of Infectious Diseases
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| Relação: |
10.1016/j.bjid.2016.07.015
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Infectious Diseases v.20 n.6 2016
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| Direitos: |
info:eu-repo/semantics/openAccess
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