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Provedor de dados:  BJMBR
País:  Brazil
Título:  Antioxidant activity of the microalga Spirulina maxima
Autores:  Miranda,M.S.
Cintra,R.G.
Barros,S.B.M.
Mancini-Filho,J.
Data:  1998-08-01
Ano:  1998
Palavras-chave:  Microalgae antioxidant activity Spirulina maxima phenolic compounds ß-carotene <
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-tocopherol
Resumo:  Spirulina maxima, which is used as a food additive, is a microalga rich in protein and other essential nutrients. Spirulina contains phenolic acids, tocopherols and ß-carotene which are known to exhibit antioxidant properties. The aim of the present study was to evaluate the antioxidant capacity of a Spirulina extract. The antioxidant activity of a methanolic extract of Spirulina was determined in vitro and in vivo. The in vitro antioxidant capacity was tested on a brain homogenate incubated with and without the extract at 37oC. The IC50 (concentration which causes a 50% reduction of oxidation) of the extract in this system was 0.18 mg/ml. The in vivo antioxidant capacity was evaluated in plasma and liver of animals receiving a daily dose of 5 mg for 2 and 7 weeks. Plasma antioxidant capacity was measured in brain homogenate incubated for 1 h at 37oC. The production of oxidized compounds in liver after 2 h of incubation at 37oC was measured in terms of thiobarbituric acid reactant substances (TBARS) in control and experimental groups. Upon treatment, the antioxidant capacity of plasma was 71% for the experimental group and 54% for the control group. Data from liver spontaneous peroxidation studies were not significantly different between groups. The amounts of phenolic acids, <FONT FACE="Symbol">a</FONT>-tocopherol and ß-carotene were determined in Spirulina extracts. The results obtained indicate that Spirulina provides some antioxidant protection for both in vitro and in vivo systems.
Tipo:  Info:eu-repo/semantics/other
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000800007
Editor:  Associação Brasileira de Divulgação Científica
Relação:  10.1590/S0100-879X1998000800007
Formato:  text/html
Fonte:  Brazilian Journal of Medical and Biological Research v.31 n.8 1998
Direitos:  info:eu-repo/semantics/openAccess
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