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Provedor de dados:  BJMBR
País:  Brazil
Título:  Flow rate, pH and calcium concentration of saliva of children and adolescents with type 1 diabetes mellitus
Autores:  Moreira,A.R.
Passos,I.A.
Sampaio,F.C.
Soares,M.S.M.
Oliveira,R.J.
Data:  2009-08-01
Ano:  2009
Palavras-chave:  Type 1 diabetes mellitus
Saliva pH
Salivary flow rate
Resumo:  Alterations in salivary parameters may increase the caries risk in diabetic children, but, contradictory data on this issue have been reported. The aims of this study were to compare salivary parameters (flow rate, pH and calcium concentration) between healthy and type 1 diabetes mellitus (T1DM) individuals. The sample consisted of 7- to 18-year-old individuals divided into two groups: 30 subjects with T1DM (group A) and 30 healthy control subjects (group B). Fasting glucose levels were determined. Unstimulated and stimulated saliva was collected. The pH of unstimulated saliva was measured with paper strips and an electrode. Calcium concentrations in stimulated saliva were determined with a selective electrode. Group A individuals had inadequate blood glucose control (HbA1C >9%), with means ± SD unstimulated salivary flow rate of 0.15 ± 0.1 mL/min compared to 0.36 ± 0.2 mL/min for group B (P < 0.01). Stimulated salivary flow rate was similar by both groups and above 2.0 mL/min. Saliva pH was 6.0 ± 0.8 for group A and significantly different from 7.0 ± 0.6 for group B (P < 0.01). Salivary calcium was 14.7 ± 8.1 mg/L for group A and significantly higher than 9.9 ± 6.4 mg/L for group B (P < 0.01). Except for elevated calcium concentrations in saliva, salivary parameters favoring caries such as low saliva pH and unstimulated salivary flow rate were observed in T1DM individuals.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000800003
Editor:  Associação Brasileira de Divulgação Científica
Relação:  10.1590/S0100-879X2009005000006
Formato:  text/html
Fonte:  Brazilian Journal of Medical and Biological Research v.42 n.8 2009
Direitos:  info:eu-repo/semantics/openAccess
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