| Registro completo |
| Provedor de dados: |
BJMBR
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| País: |
Brazil
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| Título: |
Regulation of the renal proximal tubule second sodium pump by angiotensins
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| Autores: |
Caruso-Neves,C.
Rangel,L.B.A.
Lara,L.S.
Lopes,A.G.
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| Data: |
2001-08-01
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| Ano: |
2001
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| Palavras-chave: |
Na+-ATPase
Angiotensin II
Angiotensin-(1-7)
Furosemide
Proximal tubule
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| Resumo: |
For several years it was believed that angiotensin II (Ang II) alone mediated the effects of the renin-angiotensin system. However, it has been observed that other peptides of this system, such as angiotensin-(1-7) (Ang-(1-7)), present biological activity. The effect of Ang II and Ang-(1-7) on renal sodium excretion has been associated, at least in part, with modulation of proximal tubule sodium reabsorption. In the present review, we discuss the evidence for the involvement of Na+-ATPase, called the second sodium pump, as a target for the actions of these compounds in the regulation of proximal tubule sodium reabsorption.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000800015
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| Editor: |
Associação Brasileira de Divulgação Científica
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| Relação: |
10.1590/S0100-879X2001000800015
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| Formato: |
text/html
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| Fonte: |
Brazilian Journal of Medical and Biological Research v.34 n.8 2001
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| Direitos: |
info:eu-repo/semantics/openAccess
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