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Provedor de dados:  BJMBR
País:  Brazil
Título:  Dyspnea perception in cystic fibrosis patients
Autores:  Ziegler,B.
Fernandes,A.K.
Sanches,P.R.S.
Junior,D.P. Silva
Thomé,P.R.O.
Dalcin,P.T.R.
Data:  2013-10-01
Ano:  2013
Palavras-chave:  Cystic fibrosis
Dyspnea perception
Pulmonary function test
Six-min walk test
Inspiratory resistive load testing
Resumo:  We evaluated dyspnea perception in cystic fibrosis patients compared with normal subjects, during an inspiratory resistive loading test and 6-min walk test. We also evaluated the correlation between dyspnea scores induced by resistive loads and by the 6-min walk test. In this prospective, cross-sectional study, 31 patients with cystic fibrosis (≥15 years of age) and 31 age-, gender-, and ethnicity-matched healthy volunteers (20 females and 11 males per group) underwent inspiratory resistive loading, spirometry, and the 6-min walk test. As the magnitude of the inspiratory loads increased, dyspnea scores increased (P<0.001), but there was no difference between groups in dyspnea score (P=0.654). Twenty-six (84%) normal subjects completed all the resistive loads, compared with only 12 (39%) cystic fibrosis patients (P<0.001). Dyspnea scores were higher after the 6-min walk test than at rest (P<0.001), but did not differ between groups (P=0.080). Post-6-min walk test dyspnea scores correlated significantly with dyspnea scores induced by resistive loads. We conclude that dyspnea perception induced in cystic fibrosis patients by inspiratory resistive loading and by 6-min walk test did not differ from that induced in normal subjects. However, cystic fibrosis patients discontinued inspiratory resistive loading more frequently. There were significant correlations between dyspnea perception scores induced by inspiratory resistance loading and by the 6-min walk test. This study should alert clinicians to the fact that some cystic fibrosis patients fail to discriminate dyspnea perception and could be at risk for delay in seeking medical care.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001000897
Editor:  Associação Brasileira de Divulgação Científica
Relação:  10.1590/1414-431X20133139
Formato:  text/html
Fonte:  Brazilian Journal of Medical and Biological Research v.46 n.10 2013
Direitos:  info:eu-repo/semantics/openAccess
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