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Provedor de dados:  BJMBR
País:  Brazil
Título:  Linear and nonlinear analysis of heart rate variability in healthy subjects and after acute myocardial infarction in patients
Autores:  Kunz,V.C.
Borges,E.N.
Coelho,R.C.
Gubolino,L.A.
Martins,L.E.B.
Silva,E.
Data:  2012-05-01
Ano:  2012
Palavras-chave:  Myocardial infarction
Heart rate variability
Autonomic nervous system
Spectral analysis
Nonlinear dynamics
Resumo:  The objectives of this study were to evaluate and compare the use of linear and nonlinear methods for analysis of heart rate variability (HRV) in healthy subjects and in patients after acute myocardial infarction (AMI). Heart rate (HR) was recorded for 15 min in the supine position in 10 patients with AMI taking β-blockers (aged 57 ± 9 years) and in 11 healthy subjects (aged 53 ± 4 years). HRV was analyzed in the time domain (RMSSD and RMSM), the frequency domain using low- and high-frequency bands in normalized units (nu; LFnu and HFnu) and the LF/HF ratio and approximate entropy (ApEn) were determined. There was a correlation (P < 0.05) of RMSSD, RMSM, LFnu, HFnu, and the LF/HF ratio index with the ApEn of the AMI group on the 2nd (r = 0.87, 0.65, 0.72, 0.72, and 0.64) and 7th day (r = 0.88, 0.70, 0.69, 0.69, and 0.87) and of the healthy group (r = 0.63, 0.71, 0.63, 0.63, and 0.74), respectively. The median HRV indexes of the AMI group on the 2nd and 7th day differed from the healthy group (P < 0.05): RMSSD = 10.37, 19.95, 24.81; RMSM = 23.47, 31.96, 43.79; LFnu = 0.79, 0.79, 0.62; HFnu = 0.20, 0.20, 0.37; LF/HF ratio = 3.87, 3.94, 1.65; ApEn = 1.01, 1.24, 1.31, respectively. There was agreement between the methods, suggesting that these have the same power to evaluate autonomic modulation of HR in both AMI patients and healthy subjects. AMI contributed to a reduction in cardiac signal irregularity, higher sympathetic modulation and lower vagal modulation.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000500011
Editor:  Associação Brasileira de Divulgação Científica
Relação:  10.1590/S0100-879X2012007500025
Formato:  text/html
Fonte:  Brazilian Journal of Medical and Biological Research v.45 n.5 2012
Direitos:  info:eu-repo/semantics/openAccess
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